Pituitary tumors are the most common primary intracranial neoplasms. Although most pituitary tumors are considered typically benign, others can cause severe and progressive disease. The principal aims of pituitary tumor treatment are the elimination or reduction of the tumor mass, normalization of hormone secretion and preservation of remaining pituitary function. In spite of major advances in ...

Pituitary tumors are rare tumors (less then 10%) of the central nervous system (CNS), which malignicity depends on their localization, meanwhile, their biological nature is benign. The diameter they have is mostly less then 10 mm (microadenomas), but sometimes could be 10 mm (macroadenomas) to 5 cm and more and then are usually nonfunctional (about 20% of all pituitary tumors). Clinical presenc...

The objective of this research work is to classify brain tumor images into 4 different classes by using Convolutional Neural Network (CNN) algorithm i.e. a deep learning method with VGG16 architecture. four are pituitary, glioma, meningioma, and no tumor. dataset used for publicly available MRI Image 7023 images. methodology followed in project includes data pre-processing, model building, eval...

Most pituitary tumors are benign conditions and rarely malignant. These divided into secretory non-secretory based on the tumor’s capability of secreting hormones. A study conducted in UK showed a prevalence 77.6 adenoma cases out 100000 people.

During a 5-year experience with 32 adrenal tumors with different basic problems in the Department of Endocrinology , Taleghani Hospital, 25 were found pituitary dependent Cushing's syndrome, "Cushing's disease." The treatment of patients with Cushing's disease depends on the presence or absence of pituitary tumor. Ifno pituitary tumor is demonstrated, irradiation can be given to the pituit...

To date, tumors, the second cause of death worldwide, are a modern medicine plight. The development rapid, cost-effective and reliable prevention diagnostics tools is mandatory to support clinicians ensure patients’ adequate intervention. Pituitary tumors class neoplasm, which calls for suitable ad hoc diagnostic tools. Recently, microwaves have gained interest as non-ionizing, non-invasive val...

BACKGROUND Colocalization analysis of confocal fluorescence and electron microscopy (EM) are important tools to detect the expression of multiple anterior pituitary hormones within the same cell. Heterozygous (Men1+/-) mice developed pituitary tumors, mostly reported somatolactotrophinomas and ACTH secreting pituitary adenomas but also nonfunctioning tumors. The aim of the study was to run immu...

BACKGROUND Pituitary tumors are a common form of endocrine neoplasia. However few studies assessed the expression of the principal cyclin regulating checkpoint exit, cyclin D1. Cyclin D1 expression in pituitary tumors and its possible relation to MIB-1 and p27/Kip1 labeling indices (LIs) was explored. DESIGN We studied a total of 199 pituitaries, including normal pituitaries (n=7), pituitary ...

Research performed on the pituitary has proven that cytokines play an important role in maintaining pituitary physiology, affecting not only cell proliferation but also hormone secretion. The effects of cytokines can be autocrine or paracrine. This review gives an overview on the effects of the most studied cytokines in the pituitary. Special interest is focused on interleukin-6 (IL-6) because ...

Simultaneous occurrence of morphological distinct, discreet intracranial tumors sharing the same cell lineage is a rarity. Pituitary tumors and craniopharyngiomas share a common lineage. Simultaneous occurrence of these two tumors in the same patient is rare and has been reported only nine times so far (Table 1). While pituitary tumours are centred in the sella, craniopharyngiomas may occur any...