AIM To determine whether and in what concentrations the underground waters, stream waters, spring water, and tap water from the Zagreb area contain phthalates -- compounds used as plastic softeners, which have recently been ascribed carcinogenic, mutagenic, and teratogenic effects. METHOD The presence of dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), benzylbutyl p...

Phthalates are plastic-derived contaminants that ubiquitous in natural environments and function as pro-oxidants. The extent to which phthalates bioaccumulate wild animals associations with oxidative stress poorly understood. Here, we describe relationships between maternally-derived phthalates, lipid peroxidation (malondialdehyde, MDA) the dietary antioxidant α-tocopherol eggs of European herr...

surface waters, especially natural rivers always act as receiving waters for various kinds oforganic contaminants from municipal and industrial wastewaters, agricultural activities, organic chemicals inuse, non-point source pollutions. due to their toxicity, persistency and wide diffusion, polychlorinatedbiphenyls (pcbs), pesticides, phthalates, polycyclic aromatic hydrocarbons (pah) and their ...

A study on the rapid identification of phthalates in polymer materials has been conducted by employing gas chromatography-mass spectrometry coupled with a pyrolyzer (Py-GC/MS). Since Py-GC/MS does not require any complex solvent-extraction process, a rapid screening of phthalates should be possible. In this study, polymer samples were directly introduced into the pyrolyzer in order to thermally...

This work investigated the toxicity of two isomeric alkylphthalates, i.e., di-n-octyl phthalate (DOP) and di-2-ethylhexyl phthalate (DEHP) to two model bacteria, Escherichia coli (E. coli) and Bacillus subtilis (B. subtilis), which have been previously used to study the toxicity of environmental pollutants. Microcalorimetry was used as the key analytical tool alongside scanning electron microsc...

BACKGROUND Cancer research is a national and international priority, with the efficiency and effectiveness of current anti-tumor therapies being one of the major challenges with which physicians are faced. OBJECTIVE To assess the impact of exposure to tobacco smoke, arsenic, and phthalates on cervical cancer treatment. METHODS We investigated 37 patients with locally advanced cervical carci...

Phthalates are a family of multifunctional chemicals widely used in personal care and other consumer products. The ubiquitous use of phthalates results in human exposure through multiple sources and routes, including dietary ingestion, dermal absorption, inhalation, and parenteral exposure from medical devices containing phthalates. We explored the temporal variability over 3 months in urinary ...

BACKGROUND Phthalic acid esters are widely used in the manufacture of plastics. Numerous studies have shown that these phthalates impair testicular testosterone production in the rat. However, the scarce and contradictory data concerning humans have cast doubt over whether these compounds are also anti-androgenic in man. We therefore investigated the direct effects of di-(2-ethylhexyl) phthalat...

Phthalates are industrial chemicals widely used in many commercial applications. The general population is exposed to phthalates through consumer products as well as through diet and medical treatments. To determine whether environmental levels of phthalates are associated with altered DNA integrity in human sperm, we selected a population without identified sources of exposure to phthalates. O...