Wong, Y. K., Shuttleworth, G. R., and Wood, B. S. B. (1972). Archives of Disease in Childhood, 47, 241. Effect of albumin administration on phototherapy for neonatal jaundice. Two clinical trials were designed to test the effect of albumin administration before phototherapy for non-haemolytic neonatal jaundice. The first with 18 hours of phototherapy showed that the albumin-treated group (23 in...

From 105 808 neonates born at ≥35 weeks’ gestation at 1 of 17 Kaiser Permanente Northern California hospitals between 2012 and 2014, Chang et al 9 identified a cohort of 7048 newborns treated with phototherapy. The objective of the study was to identify predictors of “rebound, ” defined as a return to treatment threshold levels within 72 hours of discontinuation of a neonate’s first round of ph...

OBJECTIVE Jaundice is a common problem in neonatal period. Phototherapy is the most common treatment for neonatal jaundice. The purpose of this study was to determine the effect of adding white plastic cover around the phototherapy unit on hyperbilirubinemia in full term neonates with jaundice. METHODS In this randomized controlled trial, over 12 months (October 2009 - September 2010), 182 te...

AIM To determine the incidence of post-phototherapy neonatal plasma total bilirubin (PTB) rebound. METHODS A prospective clinical survey was performed on 226 term and near-term neonates treated with phototherapy in the well baby nursery of the Shaare Zedek Medical Center from January 2001 to September 2002. Neonates were tested for PTB 24 hours (between 12 and 36 hours) after discontinuation ...

Jaundice is one of the most common conditions which requires medical attention in neonates. In addition to the short-term side effects, phototherapy may result in DNA damage. In this study the extent of DNA damage was assessed before and after phototherapy in cases with neonatal jaundice by single cell gel electrophoresis (Comet Assay). Eighty babies with neonatal jaundice were chosen for the s...

OBJECTIVE To compare the effectiveness of single (1 panel) vs. double (2 panels) phototherapy in reducing nonhemolytic hyperbilirubinemia in term newborns. METHODS Term newborns with hyperbilirubinemia were prospectively randomized to receive double or single phototherapy. Bilirubin levels were measured at admission and at 12-hour intervals, as well as at a follow-up 48 hours after discharge....

Background: Jaundice is one of the most common problems occurring in the neonatal period. It is commonly managed by phototherapy with its inherent complications. However, this treatment modality may itself result in the development of hypocalcaemia and create serious complications including convulsion and related conditions. Objective: To determine the effect of phototherapy on serum calcium le...

OBJECTIVES The American Academy of Pediatrics provides little guidance on when to discontinue phototherapy in newborns treated for hyperbilirubinemia. We sought to develop a prediction rule to estimate the probability of rebound hyperbilirubinemia after inpatient phototherapy. METHODS Subjects for this retrospective cohort study were infants born in 2012 to 2014 at ≥35 weeks' gestation at 16 ...

BACKGROUND Special blue tube lights of standard length are used in most neonatal units to deliver phototherapy. Of late, special blue compact fluorescent lamp phototherapy equipments have been introduced in India, which are claimed to be better than standard tube lights. AIM To compare special blue compact fluorescent lamp (CFL) phototherapy with special blue standard-length tube lights (STL)...

BACKGROUND The existing therapeutic methods for neonatal jaundice are costly, time-consuming and potentially risky. Zinc salts can reduce phototherapy duration by precipitating unconjugated bilirubin in the intestine (bilirubin and zinc can form a complex in physiologic pH); however, zinc toxicity is an issue that must be considered since theoretically bilirubin reduction by phototherapy may in...