background: in neutron interaction with matter and reduction of neutron energy due to multiple scatterings to the thermal energy range, increasing the probability of thermal neutron capture by neutron captures makes dose enhancement in the tumors loaded with these materials.   objective: the purpose of this study is to evaluate dose distribution in the presence of  10 b ,  157 gd  and  33 s  ne...

Introduction: Neutrons have many applications in various fields, such as medicine. The important application of neutron in medical science is in Boron Neutron Capture Therapy (BNCT). Because of this, determination of neutron dose and flux is critical for the health maintaining of workers and patients exposed to this beam. The neutron radioisotope sources produce gamma rays in ...

The use of epithermal neutron beam in clinical trials of Boron Neutron Capture Therapy for patients with malignant brain tumors had been carried out for half a decade at the Brookhaven's Medical Reactor. The decision to permanently close this reactor in 2000 cut short the efforts to implement a new conceptual design to optimize this beam in preparation for use with possible new BNCT protocols. ...

in this work, we had examined 7 different types of neutron sources -an isotropic point source, sending 14.1(mev) monoenergetic neutrons ,an spherical source with 30 micron radius sending 14.1 (mev) monoenergetic neutrons, and a 30 micron radius spherical source having gaussian fusion energy spectrum from a d-t fusion, with different bandwidths -1,10,50,100 and 1000 kev and investigated 5 differ...

objective: using megavoltage photons generated by medical linear accelerator is a common modality for the treatment of malignant. the crucial problem for using photon beams >8mv is the photoneutron yields that increase the risk of secondary cancer that treated with high-energy photon beams. the contaminated neutrons produced in different components of the accelerator head and rely on many param...

introduction bnct is an effective method to destroy brain tumoral cells while sparing the healthy tissues. the recommended flux for epithermal neutrons is 109 n/cm2s, which has the most effectiveness on deep-seated tumors. in this paper, it is indicated that using d-t neutron source and optimizing of beam shaping assembly (bsa) leads to treating brain tumors in a reasonable time where all iaea ...

background: prompt gamma neutron activation analysis (pgnaa) is known as a non-invasive technique capable of measuring elemental concentration in voluminous samples in a short period of time. also it is a valuable diagnostic tool for total body elemental measurements. 252cf and 241am-be sources which are usually used in this method, generate not only neutrons, but also emit high-energy and unwa...

Background: The amount of average dose enhancement in tumor loaded with 10B may vary due to various factors in boron neutron capture therapy.Objective: This study aims to evaluate dose enhancement in tumor loaded with 10B under influence of various factors and investigate the dependence of this dose enhancement on neutron spectra changes.Material and Methods: In this simulation stud...