L-type Ca2+ channel currents were recorded from myocytes isolated from bovine pial and porcine coronary arteries to study the influence of changes in intracellular pH (pHi). Whole cell ICa fell when pHi was made more acidic by substituting HEPES/NaOH with CO2/bicarbonate buffer (pHo 7.4, 36 degrees C), and increased when pHi was made more alkaline by addition of 20 mM NH4Cl. Peak ICa was less p...

Blockade of phagocytosis and selective elimination of macrophages (m phi s) are generally accepted procedures for gaining knowledge about the function of m phi s in vivo. This study demonstrates that intravenous injection of gadolinium chloride (GdCl3) not only blocks phagocytosis by rat liver m phi s (Kupffer cells) but also selectively eliminates the large m phi s situated in the periportal z...

We motivate and define $$\Phi $$ -energy density, -energy, -harmonic maps stable maps. Whereas harmonic or p-harmonic can be viewed as critical points of the integral first symmetric function $$\sigma _1$$ a pull-back tensor, second _2$$ tensor. By an extrinsic average variational method in calculus variations [cf. Howard Wei (Trans Am Math Soc 294:319–331, 1986), Yau (J Geom Anal 4(2):247–272,...

The interaction between phytochrome photoequilibrium (phi) and photon flux in the photoregulation of anthocyanin production under prolonged irradiation was studied in seedlings of Brassica oleracea L. and Lycopersicon esculentum Mill. In cabbage, anthocyanin production increases with decreasing phi, reaching a maximum at the lowest value (phi = 0.13) used in this study; in tomato, the extent of...

A method was developed in this study to measure the intracellular pH (pHi) of Dictyostelium discoideum cells with a pH-sensitive fluorescence dye, carboxyfluorescein dibutyrate, and the pHi values of cells on the stalk and spore pathways were compared. The pHi of prestalk cells was lower than that of prespore cells by approximately 0.3 pH unit. In monolayer cultures of sporogenous mutants, whic...