In this study, we present results obtained on the diastereo- and enantioseparation of some basic natural synthetic Cinchona alkaloid analogs by applying liquid chromatographic (LC) subcritical fluid (SFC) modalities amylose cellulose tris-(phenylcarbamate)-based stationary phases using n-hexane/alcohol/DEA or CO2/alcohol/DEA mobile phase systems. Seven chiral in their immobilized form were empl...

Beckurt treated physostigmine hydrochloride with dilute potassium permanganate solution and observed separation of manganese dioxide. Since at first sight there is no reaction site for this oxidation, it was interesting to clear up the route test. Acid hydrolysis O-phenylcarbamate yielded phenolic derivative three-ring indole alkaloid hydrochloride. Now are present para-position an electrodotic...

Polysaccharides, such as cellulose and amylose, are abundant and optically active carbohydrate-based resources. Their suitably modified derivatives (for example, benzoate and phenylcarbamate derivatives) exhibit excellent resolution abilities for a wide variety of chiral compounds when applied to chiral stationary phases (CSPs) for high-performance liquid chromatography. Despite the established...

Post-translational modification of proteins with O-linked N-acetylglucosamine (O-GlcNAc) is linked the development of diabetic cardiomyopathy. We investigated whether Nkx2.5 protein, a cardiac transcription factor, is regulated by O-GlcNAc. Recombinant Nkx2.5 (myc-Nkx2.5) proteins were reduced by treatment with the O-GlcNAcase inhibitors STZ and O-(2-acetamido-2-deoxy-D-glucopyroanosylidene)-am...

The newly formed generative cell of the pollen grain of the African blood lily is spheroidal after its detachment from the pollen wall. Plastids are almost always excluded from the generative cell, while dictyosomes, mitochondria, ribosomes, endoplasmic reticulum, and microtubules are present throughout development of the cell. During the time that the generative cell is spheroidal, microtubule...