The importance of premedication for pediatric patients undergoing surgical procedures dates to the classic work of Waters,’ who believed that children were as entitled as adults to have premedication. The recommended premedication was morphine with scopolamine. Later, phenothiazines were believed to be useful as anesthetic premedications because of their sedative and vasodilator effects.2’ Thes...

A 53-year-old-man with prostate cancer underwent prostate brachytherapy one month ago. Since then, he has experienced increased urinary frequency, dysuria, perineal discomfort, reduced urinary stream velocity, and nocturia. The patient was prescribed the following medications to relieve his urinary frequency and dysuria: sulfamethoxazole/trimethoprim, ciprofloxacin, tamsulosin, methylprednisolo...

THE term "artificial hibernation" first aroused our interest in Largactfl. Huguenard (2) produces a state of "artifical hibernation," which has many of the characteristics of true hibernation, by means of a diffuse blockade c,f the whole autonomic nervous system, peripherally, at the synapses, and eentraUy. Thus the patient, his autonomic system unable to respond to injury, would be protected f...

A ntipsychotic medications were introduced in the 1950s and proved to be invaluable in the amelioration of schizophrenic symptoms. These agents gained widespread acceptance in the treatment of psychoneurologic disorders, including schizophrenia, Tourette’s syndrome, effective disorders, and dementia. Antipsychotics are also called neuroleptics because of their ability to induce a variety of neu...

Compound medications – those containing 2 or more drugs in a single tablet or capsule – are nothing new to the treatment of acute migraine headache. Butalbital-containing compounds (those blending that drug with aspirin or acetaminophen and – often – caffeine) long have been prescribed – and decried – by clinicians who treat patients with headache, and Cafergot, an ancestor of the now-popular s...

THE use of sodium nitroprusside for hypotension during plastic surgical operations has been investigated at the Queen Victoria Hospital, East Grinstead, in a series of twelve cases. An attempt has been made to compare its effectiveness with that of the pharmacological blockers, and to determine whether controls such as posture and respiration are similarly responsible for its hypotensive action...

Delavirdine is an antiretroviral drug now being used as part of combination antiretroviral therapy for the management of human immunodeficiency virus (HIV) infection [1]. It belongs to the non-nucleoside reverse transcriptase inhibitor class of drugs. These drugs are known to induce delayed-type hypersensitivity skin reactions as their commonest toxicity [2]. We would like to report a severe an...

A survey of 325 American Board of Pedodontics Diplomates was conducted to determine the use of chloral hydrate and other sedative medications in treating young, uncooperative children needing extensive operative procedures. Seventy-one per cent of the respondents returned usable surveys. Seventyeight per cent of the Diplomates indicated they use sedative agents for these patients. However, the ...