OBJECTIVE We measured the levels of mutant huntingtin (mtHtt) and total huntingtin (tHtt) in blood leukocytes from Prospective Huntington At-Risk Observational Study (PHAROS) subjects at 50% risk of carrying the Huntington disease mutation using a homogeneous time-resolved fluorescence (HTRF) assay to assess its potential as a biomarker. METHODS Peripheral blood mononuclear cells from consent...

The Pharos/Spring 2016 Ralph S. Crawshaw, MD, 1921–2014, (AΩA, New York University, 1973, alumnus); Byron A. Foster, MD, MPH, is Assistant Professor, Department of Pediatrics, University of Texas Health Science Center; Matthew Iles-Shih, MD, MPH, is a Resident Physician, Department of Psychiatry & Behavioral Sciences, University of Washington; and John Stull, MD, MPH, is Assistant Professor, De...

The large volume of user generated content, although sometimes amateurish, represents a valuable source of information for audiovisual service providers. For example, companies and organizations can efficiently get feedback from consumers observing their online interaction with social media providers. Offering accurately personalized services is possible now, since users provide more personal i...

Three Dutch organisations, Pharos, Amnesty International, and the Council for Refugees, have published Care Full – Medico-Legal Reports and the Istanbul Protocol in Asylum Procedures1 which gives a comprehensive and very detailed background on the pertinent need in asylum procedures for medicallegal reports based on the Istanbul protocol. The book is an important contribution to the European de...

Although outsourcing data to cloud storage has become popular, the increasing concerns about data security and privacy in the cloud blocks broader cloud adoption. Recent efforts have developed oblivious storage systems to hide both the data content and the data access patterns from an untrusted cloud provider. These systems have shown great progress in improving the efficiency of oblivious acce...

Questo articolo propone una riflessione sulla leggenda della fondazione di Alessandria d’Egitto attraverso le descrizioni sia del luogo che clima particolarmente favorevole città, per opera degli storici periodo greco-romano. A partire da Plutarco (Vita Alessandro), diviene sempre più evidente i versi omerici si riferiscono all’isola Pharos hanno influenzato autori successivi. Anche se allusion...