We showed recently that short-term increases in stratum corneum (SC) pH are accompanied by minor alterations in permeability barrier homeostasis and SC integrity/cohesion. Since prolonged SC neutralization more closely mirrors clinical situations (i.e., neonatal skin, occupational dermatitis conditions), we assessed here whether sustained elevations of SC pH by long-term application of 1,1,3,3-...

There is an increasing concern over the impact of human-related emissions on the acid precipitation in China. However, few measurements have been conducted so far to clarify the acid-neutralization of precipitation on a regional scale. Under a network of 10 sites across Northern China operated during a 3-year period from December 2007 to November 2010, a total of 1118 rain and snow samples were...

In this paper, an adaptive neuro fuzzy sliding mode based genetic algorithm (ANFSGA) controlsystem is proposed for a pH neutralization system. In pH reactors, determination and control of pH isa common problem concerning chemical-based industrial processes due to the non-linearity observedin the titration curve. An ANFSGA control system is designed to overcome the complexity of precisecontrol o...

Dear editor, This letter presents a practical industrial process identification scheme. More specifically, to improve the accuracy of process, decoupled scheme is developed based on neural fuzzy network and autoregressive exogenous (ARX) model, which multi-signal sources. The multiple signal sources include binary signals random signals. Experimental results pH neutralization show that identifi...

Activation of proteases in the phagosomes of neutrophils occurs by neutralization of the phagosomal pH by NADPH oxidase. In this issue, Savina et al. (2006) show that dendritic cell phagosomes also recruit NADPH oxidase but with different results. Here, the neutralization of phagosomal pH reduces protease activity, which preserves antigens for crosspresentation on class I MHC molecules.

BACKGROUND During pretreatment, hemicellulose is removed from biomass via proton-catalyzed hydrolysis to produce soluble poly- and mono-saccharides. Many kinetic models have been proposed but the dependence of rate on proton concentration is not well-defined; autohydrolysis and dilute-acid hydrolysis models apply very different treatments despite having similar chemistries. In this work, evolut...

To understand the mechanism of Saposin C-membrane binding at low pH, several molecular dynamics (MD) simulations of saposin C with 1,2-dioleoyl-sn-glycero-3-phosphatidylserine (DOPS 18; 1) or modified DOPS were performed in the default charge states at neutral pH or, based on the pKa calculations, with some protonated acidic residues to approximate low pH conditions. It was found that the elect...

A significantresearch work hasbeen carried outon m odeling,identification and controlofprocessesrepresented by W ienerm odels.Thesem odelsinclude a cascadeconnection ofa lineartim e invariantsystem and a static nonlinearity. Severalapproaches can be found in the literature to perform the identification process.In thisarticle,we describe a param etric description forthe system ,that allowsto des...

Conventional control algorithms used in pH control systems give inefficient performance, leading to use of large mixers. To improve the neutralization control process, an ANFIS based advanced controller has been proposed. In this paper, method of design of adaptive controller based on neurofuzzy technique is presented. The method uses ANFIS methodology to 1 / 4

This work presents an approximation to the modeling and identification tasks using Fuzzy Inference Systems (FIS) applied to the Benchmark Problem: pH neutralization control in industrial processes. The statement of this problem is taken from a paper that postulates the waste water pH neutralization process as a benchmark approach. The proposed model uses the Takagi-Sugeno FIS type, aiming at fu...