OBJECTIVES Exchanging amniotic fluid (AF) with perfluorocarbon (PFC) may serve as a medium for fetoscopic surgery. This study evaluates the distribution and physiologic effects of intraamniotic PFC as a medium for fetoscopy. METHODS Fetuses of 17 pregnant rabbits underwent either exchange of the AF with PFC, electrolyte solution (ES), or control. The quality of vision during fetoscopy was ass...

A challenge for cognitive neuroscience is to determine how the prefrontal cortex (PFC) contributes to the cognitive control operations that oversee thought and action. We studied the effects of damage to the lateral PFC in two types of attentional control. Subjects performed a choice reaction time task that required attention switching and processing selection. The performance of individuals wi...

The authors utilized repetitive transcranial magnetic stimulation (rTMS) in 16 normal volunteers to investigate the role of the left dorsolateral prefrontal cortex (PFC) in analogic reasoning. rTMS over the left and right PFC, over the left motor cortex, and sham stimulation over the left PFC were administered during memory and analogic reasoning conditions. rTMS over the left PFC led to a sign...

In previous studies, we reported that a single afterdischarge (AD) or repeated ADs (kindling) in the hippocampus resulted in schizophrenia-like behaviors such as hyperactivity and loss of sensorimotor gating. Given that medial prefrontal cortex (PFC) dysfunction is also found in models of schizophrenia, we hypothesized that a single AD in the PFC induces postictal hyperactivity, and PFC kindlin...

Post-focus compression (PFC), the lowering of fundamental frequency and intensity after focus, is previously found in English but not in Cantonese. This study examines the possible transfer of PFC between these two languages through bilingualism. It is found that out of ten bilingual EnglishCantonese speakers, eight have PFC in their English, but none has PFC in their Cantonese. This finding su...

Abstract In this paper, a Boost-PFC experimental prototype with dual closed-loop control is developed, which carried out by virtual-real interaction approach. Firstly, the optimized design of current inner loop and voltage outer MATLAB verified Simulink graphical virtual simulation. On basis, 250W Power Factor Correction (PFC) device was developed building hardware circuits. Through approach, e...

Previous studies on the neural correlates of perceptual awareness implicate sensory-specific regions and higher cortical regions such as the prefrontal cortex (PFC) in this process. The specific role of PFC regions is, however, unknown. PFC activity could be bottom-up driven, integrating signals from sensory regions. Alternatively, PFC regions could serve more active top-down processes that hel...

We propose a new hypothesis concerning the lateralization of prefrontal cortex (PFC) activity during verbal episodic memory retrieval. The hypothesis states that the left PFC is differentially more involved in semantically guided information production than is the right PFC, and that the right PFC is differentially more involved in monitoring and verification than is the left PFC. This "product...

We propose a new hypothesis concerning the lateralization of prefrontal cortex (PFC) activity during verbal episodic memory retrieval. The hypothesis states that left PFC is differentially more involved in semantically-guided information production than is right PFC, and that right PFC is differentially more involved in monitoring and verification than is left PFC. This production-monitoring hy...

While stressors are known to increase medial prefrontal cortex (PFC) glutamate (GLU) levels, the mechanism(s) subserving this response remain to be elucidated. We used microdialysis and local drug applications to investigate, in male Long-Evans rats, whether the PFC GLU stress response might reflect increased interhemispheric communication by callosal projection neurons. We report here that tai...