MR Sequence Cerebral malaria is a severe complication seen in approximately 2% of patients with acute Plasmodium falciparum infection. Characteristic diffuse petechial hemorrhages that were previously only seen by gross pathologic or microscopic examination, and virtually undetectable by conventional imaging modalities, were well demonstrated in a patient with cerebral malaria, with use of susc...

A 16-year-old boy, with a history of juvenile myoclonic epilepsy, which had been treated with valproic acid since he was 9 years of age, presented with bilateral periorbital rash. His family had found him in a stupor state after groaning early the previous morning. The patient had a history of morning myoclonic seizures and absence seizures, but no history of generalized tonic-clonic seizures. ...

Etiologies for diffuse alveolar hemorrhage are wide and range from infectious to vasculitis and malignant processes. Idiopathic thrombocytopenic purpura is an autoimmune disorder characterized by persistent thrombocytopenia, with a relatively indolent course in young patients, but a more complicated progression and high associated mortality in the older patients. Diffuse alveolar hemorrhage, co...

OBJECTIVE Cerebrovascular disease (CVD) is a serious complication of acute leukemia, and the underlying conditions are different from the common risk factors for CVD. The aim of this study was to characterize the clinical and pathological features of CVD in patients with acute leukemia. PATIENTS OR MATERIALS In our series of 116 autopsied cases of acute leukemia during the period between Janu...

Bevacizumab in combination with chemotherapy is now being studied for the treatment of malignant gliomas. However, the risk of intracranial hemorrhage has limited its use in patients requiring full anticoagulation for venous thrombosis. To assess the safety of using anticoagulation with bevacizumab, we conducted a retrospective review of our patients who were treated with bevacizumab while rece...

Different MR imaging patterns of cerebral fat embolism have been reported in the literature without a systematic review. Our goal was to describe the patterns, explore the relationship between disease course and the imaging patterns, and discuss the underlying mechanism. We reveal 5 distinctive MR imaging patterns: 1) scattered embolic ischemia occurring dominantly at the acute stage; 2) conflu...