BACKGROUND Pesticide self-poisoning causes one third of global suicides. Sri Lanka halved its suicide rate by banning WHO Class I organophosphorus (OP) insecticides and then endosulfan. However, poisoning with Class II toxicity OPs, particularly dimethoate and fenthion, remains a problem. We aimed to determine the effect and feasibility of a ban of the two insecticides in one Sri Lankan distric...

BACKGROUND In South Asia, up to 20% of people ingesting pesticides for self-poisoning purchase the pesticide from a shop with the sole intention of self-harm. Individuals who are intoxicated with alcohol and/or non-farmers represent 72% of such high-risk individuals. We aimed to test the feasibility and acceptability of vendor-based restrictions on pesticide sales for such high-risk individuals...

objective: the scale of the problem of poisoning is enormous hence clinico epidemiological spectrum of all poisoning cases need to explore to generate the management tool. methods: this prospective study was done at two medicine units (unit 5 and 10) of dhaka medical college hospital from july to december 2010 where all poisoning cases were seen. a total of 2890 patients were admitted out of wh...

OBJECTIVE Pesticide self-poisoning accounts for one-third of suicides worldwide, but few studies have investigated the national epidemiology of pesticide suicide in countries where it is a commonly used method. We investigated trends in pesticide suicide, and factors associated with such trends, in Taiwan, a rapidly developing East Asian country. METHODS We conducted an ecological study using...

The paper by Aardema and colleagues in this issue of the Netherlands Journal of Medicine illustrates well the problems that clinicians face with organophosphorus pesticide self-poisoning. Yet the toxicological literature’s image of this poisoning is beguilingly simple. Ingestion of an organophosphorus pesticide results in inhibition of acetylcholinesterase. The resulting build up of acetylcholi...

While precautionary efforts are being made to minimize human health problems associated with agricultural pesticides, the continued occurrence of occupational poisoning from these chemicals raises major concerns among stakeholders. Information gap on human health problems associated with pesticides poses major obstacles to making informed policy decisions, particularly in developing countries w...

This study aimed to observe the clinical curative effect of penehyclidine hydrochloride (PHC) combined with hemoperfusion in treating acute severe organophosphorus pesticide poisoning. We randomly divided 61 patients with severe organophosphorus pesticide poisoning into an experimental group (N = 31) and a control group (N = 30), and we compared the coma-recovery time, mechanical ventilation ti...

This paper aimed to characterize the rural work process in nine counties in Minas Gerais State, considering socio-demographic indicators, the land tenure structure of farm operations, and work practices related to pesticide use and poisoning Data were obtained through the Jorge Duprat Figueiredo Foundation for Workers' Safety and Occupational Medicine, which applied a questionnaire to 1,064 rur...

BACKGROUND Pesticide poisoning is an important cause of morbidity and mortality in India. OBJECTIVES To assess the oxidative damage, hemoglobin level and leukocyte count in acute organophosphorus pesticide poisoning. METHODS Plasma cholinesterase was assessed as a toxicity marker. Oxidative damage was assessed by estimating serum malondialdehyde (MDA) levels, plasma total antioxidant capaci...