We here report a case of plasmapheresis-remediable hyperinsulinemic hypoglycemia without evidence of severe insulin resistance or insulin antibodies. The clinical course and a concise review on hyperinsulinemic hypoglycemia are presented. A 44-year-old man with history of type 2 diabetes, hypertriglyceridemia, and severe dilated cardiomyopathy presented with fasting and postprandial hypoglycemi...

Despite the many benefits of bariatric surgery in patients with morbid obesity, concerns have been raised over its association with severe hyperinsulinemic hypoglycemia and nesidioblastosis following Roux-en-Y gastric bypass surgery. Cases have been described with severe post-prandial hypoglycemia with neurological symptoms following surgery. Some of these cases are recalcitrant to medical trea...

Hypoglycemia is the most common metabolic alteration in neonatal period. Most of these neonates have transient hypoglycemia. However, persistent and recurrent hypoglycemia in neonates is usually caused by endocrine or metabolic disorders. These babies require frequent glucose monitoring to prevent hypoglycemic brain injury and advanced investigations for diagnosis of underlying etiology. An app...

The present study examines the effect of concanavalin A (Con A) on the blood insulin and glucose levels of rats. Male and female rats treated with Con A (62.5-500 micrograms/kg) for three days showed a dose- and time-dependent hyperinsulinemia that lasted more than 48 h. Male rats were more sensitive to Con A. Thus, 6 h after treatment with Con A the circulating insulin levels in male rats had ...