peritoneum

BACKGROUND Meshes implanted intraperitoneally are known to cause adhesions potentially resulting in complications such as chronic pain, enterocutaneous fistula, or mesh infection. This study introduces a model for investigation of intestine-to-mesh adhesions and evaluates as to whether missing of visceral peritoneum is causative. METHODS In 18 rats, rectangular 1.5 x 2 cm patches of an uncoat...

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Alterations in proteoglycan components and histopathology of the peritoneum in uraemic and peritoneal dialysis (PD) patients.

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2009

Shiwori Osada Chieko Hamada Tetsutaro Shimaoka Kayo Kaneko Satoshi Horikoshi Yasuhiko Tomino

BACKGROUND Proteoglycans (PGs) are dominant extracellular matrices (ECMs) in the peritoneal tissues. Human peritoneal mesothelial cells synthesize small proteoglycans including decorin. Peritonitis and long-term peritoneal dialysis (PD) cause fibrotic changes in the peritoneum that result in ECM remodelling and PG synthesis. METHODS Twenty-five peritoneal tissues from eight patients at initia...

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