a common cause of peripheral nerve injury is trauma. the positive effect of antioxidants on the improvement of nerve regeneration has currently become a focus of attention. in this experiment, the effect of intraperitoneal administration of ubiquinone (coq10) on an acute experimentally sciatic nerve crush was studied in a rat model. forty-five male wistar rats, weighing between 160-180 g were u...

introduction: multiple sclerosis (ms) is generally known as a manageable but not yet curable autoimmune disease affecting central nervous system. a potential therapeutic approach should possess several properties: prevent immune system from damaging the brain and spinal cord, promote differentiation of oligodendrocyte progenitor cells (opcs) into mature oligodendrocytes to produce myelin, preve...

background: human peripheral blood nk cells constitutively express cd56 and cd16 antigens. peripheral blood nk cells seem to be strongly related with decidual nk cells, and may reflect the decidual nk cell functional status. there are varied reports concerning the relationship between nk cell cytotoxicity in women with recurrent spontaneous abortion. objective: to study nk activity in women wit...

objective: stevioside is a natural non-caloric sweetener which has been reported to have anti-inflammatory activity.  the aim of  the present study was to examine in vitro and in vivo effects of  stevioside on rats  plasma levels of tumor necrosis factor- α (tnf-α),  interleukin-1β (il-1β), tnf-α and il-1β release from lipopolysaccharide(lps)-stimulated rat peripheral blood mononuclear cells (p...

conclusion in cases with critical atherosclerotic disease of anterior tibial artery, pta-based biphasic or triphasic retrograde collateral flow prevents ischemia, whereas monophasic support or no retrograde flow remains incapable. results in the patient group, 31 lower limb arteries, of total of 17 cases, were included. after compression maneuver, dpa in 11 cases (six right, five left) showed r...

from 1996 to 2002, fifty three patients with major beta-thalassemia received allogeneic peripheral blood stem cell trans plantation (pbsct). median age was 6 years .twenty two were class i, 17 class ii and 14 class iii. all of the donors were hla-identical. conditioning regimen for class i and ii patients consisted of cyclophosphamide (cy) 50 mg/kg/day for 4 days + busulfan (bu) 3.5 mg/kg for 4...

excessive scarring; paralleling the process in tendon reconstruction of the hand. inspired by the advantages of the two-stage technique in tendon grafting and with encouraging preliminary results, we aimed to investigate the two-stage nerve grafting technique as an alternative method of secondary nerve repair. methods:  thirty female rats (~200 g) were randomly distributed into two groups (n=15...

introduction: currently, neuroresearchers report that the median nerve shows severity-correlated intracarpal enlargement in idiopathic carpal tunnel syndrome (cts) as a most common peripheral neuropathic disorder. the purpose of this paper was to investigate ultrasonography morphological findings in patients with idiopathic cts and comparing some physical properties such as age, gender, bmi wit...

introduction: according to the high incidence of bell's palsy (ifp) and lack of clinical data regarding different aspects of disease, the present study investigated 121 iranian patients with peripheral facial paralysis referred to the emergency department. methods: in this retrospective study, all patients with peripheral facial paralysis, referred to the emergency department of poursina hospit...

background: variations of the brachial plexus are common and a better awareness of the variations is of crucial importance to achieve successful results in its surgical procedures. the aim of the present study was to evaluate the anatomical variations of the brachial plexus in adult cadavers.   methods: bilateral upper limbs of 32 fresh cadavers (21 males and 11 females) consecutively referred ...