OBJECTIVES The purpose of this study was to evaluate benzodiazepine receptor expression on leukocytes from patients with symptomatic or silent myocardial ischemia. BACKGROUND Silent myocardial ischemia is frequently observed in patients with coronary artery disease. Pain can be effectively controlled by various endogenous mechanisms. Benzodiazepines and their receptors play key roles in pain,...

OBJECTIVE In common peripheral neuropathies, sensory symptoms usually prevail over motor symptoms. This predominance of sensory symptoms may result from higher sensitivity of sensory axons to ischemia. METHODS We measured median nerve compound sensory action potentials (CSAPs), compound muscle action potentials (CMAPs), and excitability indices in five healthy subjects during forearm ischemia...

Left atrial thrombus (LAT) formation is a feared complication of fibrillation, as it can lead to thromboembolic stroke or thromboembolism another peripheral region causing ischemia. Despite therapeutic anticoagulation, recurrence thrombi still possible, although unlikely. Prevention strategies may include reducing left size along with treatment by surgical removal. We present case patient large...

Abstract Background Peripheral arterial disease (PAD) affects millions of people and compromises quality life. Critical limb ischemia (CLI), which is the most advanced stage PAD, can cause nonhealing ulcers strong chronic pain, it shortens patients’ life expectancy. Cell-based angiogenic therapies are becoming a real therapeutic approach to treat CLI. Pericytes cells that surround vascular endo...

diabetic macular edema (dme) is an important cause of blindness in the working population and is currently challenging to treat. current interventions include focal laser or intravitreal injections. this article outlines a new treatment protocol based on the concept that peripheral ischemia is the introduction to angiogenesis, that will ultimately gather its momentum at the fovea. performing ex...

Digital ischemia is a rare paraneoplastic phenomenon associated with various malignancies, especially adenocarcinomas. We reported a case of digital ischemia onset during treatment with capecitabine + oxaliplatin, letrozole and epoetin-beta in a 75-year old woman with colon and breast cancer and a secondary hepatic lesion. A literature review disclosed 68 cases of solid neoplasms associated wit...