Serial cultivation of cell lines derived from lung, testis, periorbital and tumor tissues of a green turtle (Chelonia mydas) with fibropapillomas resulted in the in vitro formation of tumor-like cell aggregates, ranging in size from 0.5 to 2.0 mm in diameter. Successful induction of tumor-like aggregates was achieved in a cell line derived from lung tissue of healthy green turtles, following in...

Cellulitis is a rare manifestation of meningococcal disease. We describe the case of a previously healthy 4-month-old female infant who developed periorbital cellulitis associated with meningococcal meningitis. Pediatrics 2005;116:e874–e875. URL: www.pediatrics.org/ cgi/doi/10.1542/peds.2005-0694; meningitis, meningococcal disease. ABBREVIATION. CSF, cerebrospinal fluid. Periorbital cellulitis ...

Introduction Tumor necrosis factor receptor-1 associated periodic syndrome (TRAPS) is a periodic fever syndrome, characterized by recurrent fever attacks associated with rashes, musculoskeletal and abdominal pain, and periorbital edema. In few patients TNF inhibitors have been shown to be effective, however, their efficacy tends to decrease over time [1-4]. Anti-IL-1 treatments have also been u...

Adult-onset Still’s disease (AOSD) is a systemic inflammatory disorder of unknown etiology that is characterized by high-spiking fever, arthralgia, sore throat, and skin rash. The typical rash of AOSD is an evanescent, salmon-colored erythema, which is considered to be the major diagnostic criterion. Recently, other cutaneous manifestations of AOSD, such as persistent plaque and urticaria, have...

Two patients developed bilateral, periorbital edema after initiating positive airway pressure (PAP) therapy with a full face mask. The periorbital edema was more pronounced in the morning and would dissipate throughout the day. This phenomenon seemed to be correlated with the direct pressure of the full face mask, which may have impaired lymphatic and venous drainage. To test this hypothesis, e...

P eriorbital rejuvenation is a topic of particular interest to aesthetic surgeons, as aging changes often occur first around the eyelids, and periorbital surgery can improve both function and cosmesis. Ahead, the authors describe an approach to the periorbital aesthetic unit to treat the eyebrow, upper eyelid, lateral canthus, lower eyelid, and midface through a single upper eyelid blepharoplas...

Conflicts of interests: none Financial support: none ABS TRACT Periorbital hyperchromia (dark eye circles) is a recurrent complaint in dermatologic consultations, as it interferes with patients’ self esteem. The eyes are central in the communication process, and dark eye circles are very noticeable and make the face look tired; thus they have a considerable impact on patients’ quality of life. ...