We report a case of large radicular cyst progression related to endodontic origin to emphasize proper intervention and follow-up for endodontic pathosis. A 25 yr old man presented with an endodontically treated molar with radiolucency. He denied any intervention because of a lack of discomfort. Five years later, the patient returned. The previous periapical lesion had drastically enlarged and i...

This case report demonstrates an unnecessary endodontic treatment of teeth with florid cemento-osseous dysplasia (FCOD) due to a misdiagnosis as periapical pathosis and emphasizes the importance of correct diagnosis to avoid unnecessary treatment. A 30-year-old woman was referred to our institution for apicoectomies of the mandibular left canine and both the lateral incisors. The periapical les...

Bacteria and their products play a primary etiological role in the initiation and perpetuation of pulpo-periapical pathosis. The biological objective of root canal treatment is eradication of bacterial load from the root canal system. Despite the fact that all measures are being taken to achieve this goal, failures are still being reported [1]. The ability of certain microbes to form biofilms i...

This case report describes the treatment of two immature maxillary central incisors in a 7-year-old female patient. She suffered complicated crown fracture because of trauma, and the root formation was incomplete. White mineral trioxide aggregate (MTA) was selected as the pulp-capping material after cervical pulpotomy to preserve the pulp tissue vitality and achieve maturogenesis. Follow-up eva...

The spectrum of endodontic pathosis includes many conditions for which dentists and endodontists determine that it is appropriate to prescribe antibiotics. Some of these conditions involve purely an inflammatory reaction, and some involve various stages of infection. This infection may be localized to the pulp and periapical tissues, and it may be spreading to regional lymph nodes, or systemica...

AIM The aim of this study was to determine tumor necrosis factor-alpha (TNF-alpha) levels in periapical exudates and to evaluate their relationship with radiological findings. METHODOLOGY Periapical exudates were collected from root canals of 60 single-rooted teeth using absorbent paper points. TNF-alpha levels were determined by enzyme-linked immunosorbent assays. The samples were divided in...

this case report describes the treatment of two immature maxillary central incisors in a 7- year-old female patient. she suffered complicated crown fracture because of trauma, and the root formation was incomplete. white mineral trioxide aggregate (mta) was selected as the pulp-capping material after cervical pulpotomy to preserve the pulp tissue vitality and achieve maturogenesis. follow-up ev...

Platelet-rich fibrin (PRF) created by Choukroun's protocol concentrates most platelets and leukocytes from a blood harvest into a single autologous fibrin biomaterial. However, no current data is available concerning the use of PRF for the treatment of periapical lesions. Two cases of radicular cysts were reported using an interdisciplinary approach, including regular endodontic therapy followe...