Background Allergens from house dust mites are perennial and also have enzymatic nature. They are commonly found in bedding, mattresses, pillows, bedroom floor and living room. In addition, they are often associated with sensitization and intensification in the symptoms of allergic rhinitis and asthma for susceptible individuals. Household dogs are continuously in contact with the ecological ni...

Identification of the most common aeroallergens to which patients are sensitized in a specific area is important in the diagnosis and treatment of allergic rhinitis. The aim of this cross-sectional study was to investigate the pattern of skin prick test reactivity to various aeroallergens among allergic rhinitis patients attending outpatient clinics in Amman, Jordan. Skin prick test with 18 sta...

BACKGROUND House dust mites (HDMs) such as Dermatophagoides farinae and D. pteronyssinus represent major causes of perennial allergy. HDM proteomes are currently poorly characterized, with information mostly restricted to allergens. As of today, 33 distinct allergen groups have been identified for these 2 mite species, with groups 1 and 2 established as major allergens. Given the multiplicity o...

BACKGROUND Solidago virgaurea (goldenrod) is a perennial weed from which no allergens have been identified. A high latex content in its leaves has been reported. Although not an airborne allergen, it may be an important occupational sensitizer. OBJECTIVE To identify allergenic proteins in goldenrod and to determine whether they cross-react with Hevea brasiliensis latex. METHODS Potential cr...

A characteristic feature of type I allergies is the presence of allergen-specifi c immunoglobulin E (sIgE) [1,2]. Thus, the detection of sIgE, in addition to obtaining a clinical history and performing a skin prick test (SPT), is important for allergy workup. Historically, sIgE to various allergens was analyzed by radioallergosorbent test using allergen-coupled cellulose paper discs. Later on, ...

STUDY POPULATION. Subjects were 278 children (age: 5–14 years) with seasonal grass pollen-induced allergic rhinoconjunctivitis for 2 years. Allergy was confirmed by a timothy grass-specific immunoglobulin E (IgE) level of at least class 2 and a wheal diameter of 3 mm in a skin-prick test containing 5 grass pollens included in the SLIT tablet (orchard, meadow, perennial rye, sweet vernal, and ti...

Allergen specific immunotherapy remains the only means to change the natural history of allergic disease. Thanks to the recent advances in molecular biology a large spectrum of purified allergen molecules are presently routinely available for diagnostic purposes. This review represents a practical guide on how to use these new diagnostic tools in order to detect precisely the primary sensitizin...

BACKGROUND Allergen specific immunotherapy was known to be useful in the treatment of respiratory allergic disease. Local nasal immunotherapy (LNIT) offers advantages such as a good efficacy/safety ratio and a more convenient allergen delivery. The aim of this study was to assess the safety and clinical efficacy of a modified scheduling of LNIT in 32 children with allergic rhinitis due to Derma...

BACKGROUND Allergic disorders are characterized by a systemic involvement of the immune response. There is a clear link between allergic rhinitis and asthma. Bronchial hyperreactivity (BHR) may be present in rhinitics. Smaller airways may also be impaired in mild asthma. This study aimed at evaluating a group of subjects suffering from perennial allergic rhinitis alone to investigate the presen...

Multicenter Study on the Prevalence of Perennial Allergic Rhinitis and Allergy-Associated Disorders This study was aimed to determine the prevalence of perennial allergic rhinitis (PAR) using the skin test, radioallergosorbent test (RAST), or multiple allergosorbent test (MAST) and to clarify the clinical aspects of the patients diagnosed as having PAR by the questionnaire survey and rhinologic...