Background and Objective: Peganum harmala is a medicinal plant that has been used for treatment of numerous diseases including viral, bacterial and parasitic infections. Anti-proliferative and anti-tumor effects of Peganum harmala extracts and its derivatives have been reported. In the present study, cytotoxic effect of Peganum harmala seeds aquaous extract on leukemic U937 and Molt-4 cells was...

UNLABELLED BACKGROUND Biotransformation offers chemo enzymatic system to modify the compounds into their novel analogues which are difficult to synthesize by chemical methods. This paper describes the biotransformational studies of ambrox, one of the most important components of natural Ambergris (wale sperm) with fungal and plant cell culture. RESULTS Biotransformation of (-)-ambrox (1) w...

parkinson’s disease is one of the most common neurodegenerative disorders.  there are many documents about the effects of oxidative stress in parkinson’s disease etiology. angiotensin ii activates nadph dependent oxidases and causes superoxides formation.  peganum harmala l. extract, which has angiotensin converting enzyme (ace) inhibitory effect, is considered to evaluate oxidative stress inhi...

Introduction: Benign prostatic hyperplasia (BPH) is considered as a major cause of lower urinary tract symptoms (LUTS) in older men and its most common sign is nocturia. Objectives: This study aimed to determine the effect of the seeds of Peganum harmala compared with tamsulosin on alleviating urinary symptoms in patients with BPH. Patients and Methods: In this single blind clinical trial study...

BACKGROUND Leishmaniasis is one of the six most common parasitic infections in the tropical regions. There are different therapeutic modalities, however therapeutic resistance is developed and resulted in numerous problems. Therefore, evaluation of other therapeutic modalities is performed extensively. OBJECTIVES The current study aimed to compare the therapeutic response of cutaneous leishma...

While screening of selected herds of cattle (each having minimum 15 animals), 28 animals were found positive for tropical theileriosis (Theileria annulata) from a total of 260. The overall bi-monthly incidence rate was 10.8% from April-July, 2011 in Faisalabad. 89.3% and 10.71% in females and males respectively. To check breed wise prevalence, 4 out of all 28 positive animals were of Red Sindhi...