OBJECTIVE Tumors of the central nervous system are now thought to be the most common form of childhood malignancies. Previous studies suggested that delays might exist between symptom onset and the diagnosis of pediatric brain tumors. In the Maritime Provinces of Canada (New Brunswick, Nova Scotia, and Prince Edward Island), there are only two pediatric neurosurgical centers; therefore, the Mar...

in this study, 22 patients (15-75 years old) were selected and transferred to ct scan for tumor ablation. for ablations, after prep and drep under the local anesthesia and mild sedation in proper position, small incision made and special needle inserted and guided by proper direction to the core of the tumor. then, laser probe inserted through the needle and laser energy delivered. although we ...

Malignant brain tumors are the most common cause of solid cancer death in children. New targeted therapies are vital to improve treatment outcomes, but must be developed to enable trafficking across the blood brain barrier (BBB). Since activated T cells cross the BBB, cancer immunotherapy can be harnessed to unlock the cytotoxic potential of the immune system. However, standard of care treatmen...

minor trauma to the head is common in childhood and does not require any medical or surgical treatment. nevertheless, head injury in infancy and childhood is the single most common cause of death and permanent disability. measurable deficits occur even after mild to moderate head injury but are markedly greater after severe injury. they include impaired cognition, motor impairments, disruption ...