In Pb-contaminated environments, simultaneous exposure to both waterborne and dietborne Pb is likely to occur. This study examined the potential interactive effects of these two pathways in juvenile rainbow trout that were exposed to Pb in the water alone, in the diet alone, and in combination for 7 weeks. The highest waterborne Pb concentration tested (110μgL(-1)) was approximately equivalent ...

BACKGROUND AND OBJECTIVE CD34+ hematopoietic progenitor cells (HPCs) constitute a heterogeneous population both in size and in immunological features. Lack of CD38, HLA-DR and lineage committed antigens as well as the co-expression of Thy-1 (CDw90) and c-kit receptor (CD117), are able to identify the so-called stem cells. A flow cytometric study was carried out to investigate the co-expression ...

OBJECTIVE Blood lead (B-Pb), one of the most used toxicological biomarker all kind, has serious limitations. Thus, the objective is to evaluate whether plasma lead (P-Pb) is more adequate. METHODS A long-term follow-up study of five cases of lead poisoning. P-Pb was analysed by inductively coupled plasma mass spectrometry. Kinetics after end of exposure was modelled. RESULTS P-Pb at severe ...

Lead (Pb)-induced hypertension is characterized by an increase in reactive oxygen species (ROS) and a decrease in nitric oxide (NO). In the present study we evaluated the effect of L-arginine (NO precursor), dimercaptosuccinic acid (DMSA, a chelating agent and ROS scavenger), and the association of L-arginine/DMSA on tissue Pb mobilization and blood pressure levels in plumbism. Tissue Pb levels...

The Poisson-Boltzmann (PB) equation is conventionally used to model the equilibrium of bulk ionic species in different media and solvents. In this paper we study a new PoissonBoltzmann type (PB n) equation with a small dielectric parameter 2 and nonlocal nonlinearity which takes into consideration of the preservation of the total amount of each individual ion. This equation can be derived from ...

BACKGROUND Lead (Pb) is a toxic element that occurs in elevated concentrations in soils, mostly as a result of anthropogenic activities. This study assess the Pb bioavailability in soils from two areas with different contamination level using Diffusive Gradients in Thin-Films (DGT) technique, single extractions and metal contents of vegetables grown on contaminated soils. RESULTS In the area ...

The potential of 6 tree species (Leucaena leucocephala, Acacia mangium, Peltophorum pterocarpum, Pterocarpus macrocarpus, Lagerstroemia floribunda, Eucalyptus camaldulensis) for phytoremediation of Pb in sand tailings (total Pb >9850 mg kg(-1)) from KEMCO Pb mine in Kanchanaburi province, Thailand, were investigated employing a pot experiment (3 months) and field trial experiment (12 months). I...

Sander Y.A. Rodenburg, Michael F. Seidl, Dick de Ridder*, Francine Govers* 3 4 1 Laboratory of Phytopathology, Wageningen University, Droevendaalsesteeg 1, 6708 PB 5 Wageningen, The Netherlands 6 2 Bioinformatics Group, Wageningen University, Droevendaalsesteeg 1, 6708 PB 7 Wageningen, The Netherlands 8 9 * Equal contribution 10 Correspondence: 11 Francine Govers, Laboratory of Phytopathology, ...

The murine mast cell line PB-3c is dependent on interleukin 3 (IL-3) with respect to survival and proliferation. These cells also require IL-3 to display antigen-mediated serotonin release, which is coupled to a transient increase of cytosolic free calcium ([Ca2+]i). The antigen-mediated exocytosis is inhibited by phorbol 12-tetradecanoate 13-acetate (PTA), an activator of phospholipid/Ca2+-sen...