background: oxaliplatin (ox) significantly enhanced the antitumor activity of 5-fu in patients with advanced colorectal cancer and recently some phase ii trials have evaluated the feasibility and efficacy of oxaliplatin in neoadjuvant setting for treatment of locally advanced rectal cancer. on the other hand various studies have demonstrated that the overexpression of thymidylate synthase (ts) ...

cemento-ossifying fibroma is a fibro-osseous lesion that has benign neoplastic behavior. we report two cases of cemento-ossifying fibroma (cof) and review the literature in order to study the imaging findings of cof. it is almost unavoidable that diagnosis of fibrous dysplasia from cof will be complicated by the fact that some pathologic features are shared by both lesions. so the final definit...

background breast cancer is the most common cancer among women worldwide. based on the latest iranian national cancer department report, the total number of women registered with breast cancer was 6976 cases during 2007. five year survival is one of the indicators used for evaluation of the quality for care to different types of malignancies including breast cancer. objectives the aim of this s...

Background: Compression fractures are often associated with lower energy trauma and may occur in the setting of abnormal bone health genetic disorders endocrine disorders, neoplastic disease, infection, inflammatory disorders. There is no significant series literature describing prevalence or etiology pathologic pediatric compression fractures. Methods: IRB-approved retrospective study was perf...

BACKGROUND The treatment of breast cancer requires a multidisciplinary approach, and patients are often referred to a multidisciplinary cancer clinic. The purpose of the current study was to evaluate the impact of this approach on the surgical management of breast cancer. METHODS The medical records of 149 consecutive patients referred to a multidisciplinary breast cancer clinic over a 1-year...

OBJECTIVE To determine ways to improve diagnostic accuracy of multiple system atrophy (MSA), we assessed the diagnostic process in patients who came to autopsy with antemortem diagnosis of MSA by comparing clinical and pathologic features between those who proved to have MSA and those who did not. We focus on likely explanations for misdiagnosis. METHODS This is a retrospective review of 134 ...