BACKGROUND & AIMS This study aims to analyze the feasibility and predictive value of thermal tomography (TT) for monitoring early treatment response in patients with locally advanced breast cancer (LABC) receiving neoadjuvant chemotherapy (NAC). METHODS Patients with LABC who were due to receive six cycles of NAC were examined by TT prior to NAC, the second cycle of NAC, the fourth cycle of N...

PURPOSE The aim of this study was to determine the safety and pathologic response rates following neoadjuvant paclitaxel and radiation in patients with stage II/III breast cancer and to evaluate the use of sequential biopsies to allow an in vivo assessment of biological markers as potential predictive markers of response to this regimen. PATIENTS AND METHODS Patients with high-risk, operable ...

PURPOSE To investigate whether before and after chemoradiotherapy (CRT) positron emission tomography (PET) predict for pathologic response after preoperative CRT in patients with locally advanced rectal adenocarcinoma. METHODS Thirty-five patients who underwent pre-CRT and post-CRT PET scans before surgery were included. All patients were staged with endoscopic ultrasound or high resolution C...

endometrial calcification along with ossification is an uncommon clinical entity. most of the cases are asymptomatic or present with secondary infertility. endometrial ossification associated with repeated abortions has been reported very infrequently. here we report a case of endometrial calcification with ossification  due to retained fetal bony tissue in a 38 year old symptomatic female havi...

conclusions psa, psa density, and gleason score should be considered together in order to more accurately predict the adverse pathologic features of prostate cancer. methods we conducted a cross-sectional study of 105 patients with localized prostate cancer who underwent radical prostatectomy between 2006 and 2013. we recorded gleason scores and psa levels, in addition to the results of patholo...

Standardized uptake value (SUV), which is an indicator of the degree of glucose uptake in 18Ffluorodeoxy-glucose positron emission tomography (18FDG-PET), can be applied as a prognostic factor in various malignant tumors. We investigated the prognostic impact of early changes in 18FDG-PET uptake in patients with locally advanced breast cancer who received neoadjuvant chemotherapy (NAC). Methods...

PURPOSE Fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) are used to determine human epidermal growth factor receptor-2 (HER-2) status and patient eligibility for trastuzumab therapy. Using FISH and IHC, we analyzed the relationship between pathologic complete response to trastuzumab-based neoadjuvant therapy and level of HER-2 amplification in locally advanced breast ca...