PURPOSE To evaluate the psychometric characteristics of the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) in patients with age-related macular degeneration (AMD) who participated in two clinical trials. METHODS A secondary analysis of data from two randomized clinical trials was performed. NEI VFQ-25 data were collected from 1134 of 1146 patients with subfoveal choroida...

5-Formyluracil (5-foU) is a potentially mutagenic lesion of thymine produced in DNA by ionizing radiation and various chemical oxidants. Although 5-foU has been reported to be removed from DNA by Escherichia coli AlkA protein in vitro, its repair mechanisms are not fully understood. In this study, we used the borohydride trapping assay to detect and characterize repair activities for 5-foU in E...

OBJECTIVE To measure the visual functioning and quality of life in patients with uveitis. METHODS Consecutive adult patients with noninfectious uveitis were enrolled. The Medical Outcomes Study 36-Item Short Form (SF-36) and the National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) were administered by a trained interviewer. Sociodemographic and clinical data were also collecte...

conclusions based on the presence of ta systems in the majority of p. aeruginosa isolates, these could be used as a novel target for antimicrobial therapy. results our results showed that in the 174 p. aeruginosa isolates, relbe and higba were universal, but parde was less prevalent. both of the flanking regions of the parde genes in all positive isolates were amplified. the flanking regions of...

In this paper, we present a novel approach for Hindi Named Entity Identification (NEI) in a large corpus. The key idea is to harness the global distributional characteristics of the words in the corpus. We show that combining the global distributional characteristics along with the local context information improves the NEI performance over statistical baseline systems that employ only local co...

Previously, a linear relationship has been found between net energy intake (NEI) and dietary chewing index (CI) of the diet for different types of cattle. Therefore, we propose to generalize and calibrate this relationship into a new model for direct prediction of NEI by dairy cows from CI values (CINE; min/MJ of NE). Furthermore, we studied the forage-to-concentrate substitution rate in this n...

35 La problematica di un efficace approccio vaccinale nei confronti del Meningococco B (MenB) è stata superata identificando con la metodica della “reverse vaccinology” alcuni antigeni capaci di indurre una risposta verso la maggior parte dei ceppi di MenB circolanti nel mondo. Il nuovo vaccino MenB a 4 componenti (4CMenB) è stato autorizzato in Europa, Australia e Canada, ed è entrato nei cale...

PURPOSE To assess vision-specific quality of life (QOL), based on abbreviated surveys derived from the National Eye Institute Visual Function Questionnaire (NEI-VFQ), in a cohort of United States women who participated in the Study of Osteoporotic Fractures. DESIGN Prospective, observational cohort study. METHODS Age-related macular degeneration (AMD) status, based on a 3-level classificati...