The effect of grating textures on the alignment of cell shape and intracellular actin cytoskeleton has been investigated in bovine aortic endothelial cells (BAECs) cultured on a model cross-linked poly(dimethylsiloxane) (PDMS). Grating-textured PDMS substrates, having a variation in channel depths of 200 nm, 500 nm, 1 pm and 5 pm, were coated with fibronectin (Fn) to promote endothelial cell ad...

This paper presents a system for the automatic generation of Galois-field (GF) arithmetic circuits, named the GF Arithmetic Module Generator (GF-AMG). The proposed system employs a graph-based circuit description called the GF Arithmetic Circuit Graph (GF-ACG). First, we present an extension of the GF-ACG to handle GF(pm) (p ≥ 3) arithmetic circuits, which can be efficiently implemented by mult...

When all the inputs of a parallel manipulator (PM) are locked, the manipulator is usually turned into a structure. When an uncertainty singularity occurs for a PM, the latter structure is unstable or, in other words, it may undergo infinitesimal or finite motion. Hence, the investigation of the uncertainty singularities of a PM can be reduced to the instability analysis of its corresponding str...

Idiopathic inflammatory myopathies are a heterogeneous group of muscle disorders characterized by chronic muscle inflammation and progressive muscle weakness. Polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM) are the three major subsets based on distinct clinical and histopathological features. Since the pathogenesis remains unclear, therapeutic approaches actually compr...

idiopathic inflammatory myopathies are a heterogeneous group of muscle disorders characterized by chronic muscle inflammation and progressive muscle weakness. polymyositis (pm), dermatomyositis (dm) and inclusion body myositis (ibm) are the three major subsets based on distinct clinical and histopathological features. since the pathogenesis remains unclear, therapeutic approaches actually compr...

We reinvestigated the organization of the premotor cortex (PM) using intracortical microstimulation. Movements of forelimb, hindlimb, and orofacial structures were evoked from broad regions of PM that appeared to be contiguous with other motor areas. There were two principal findings: (1) the somatotopy of PM lies roughly parallel to that of the primary motor cortex (MI). Forelimb movements wer...