Malignant acanthosis nigricans is a rare paraneoplastic skin syndrome mostly associated with gastric adenocarcinoma. Florid cutaneous papillomatosis and tripe palms syndrome are considered to be abortive clinical variants of acanthosis nigricans. Clinical manifestations include pruritic, hyperkeratotic and hyperpigmented plaques with a subsequent formation of velvety papillomas in the involved ...

Papillomas are rare tumors of the respiratory tract, which are usually considered benign. We studied a male patient with adult onset of squamous papillomatosis involving both the trachea and the bronchi, with malignant degeneration. When we obtained specimens bronchoscopically, only the bronchial lesions showed carcinomatous changes. Thoracotomy demonstrated carcinoma in the tracheal lesion as ...

Squamous papillae in the vestibule are common. They were once considered to be normal variants of female anatomy, but reports of the viral aetiology of such lesions are emerging. When they are symptomatic, squamous papillae can lead to problems in sexual relationships between healthy partners. Here we report a case that responded well to treatment.

Tripe palms, which described the thickening of pamar skin with increase of normal dermatoglyphics and a peculiar velvety texture, is a specific cutaneous paraneoplastic syndrome especially related to cancers of upper aerodigestive tract. Acanthosis nigricans, and florid cutaneous papillomatosis (sudden appearance of many warty skin lesions) are the most commonly associated paraneoplastic dermat...

Here, we report a case of Cowden syndrome with an unusual clinical course of late-onset oral papillomatosis and a novel germline PTEN mutation. Cowden syndrome is the most common phosphatase and tensin homolog hamartomatous tumor syndrome. It is characterized by multiple hamartomas in the gastrointestinal tract and mucocutaneous lesions such as trichilemmomas, oral papillomatosis, facial papule...

The case of a 27-year-old male with recurrent respiratory papillomatosis including lung involvement is presented. Laryngotracheal papillomatosis with lung involvement is a rare entity associated with human papillomavirus infection. Computed tomography (CT) was essential in guiding diagnostic and therapeutic approaches. Knowledge about the findings of this disease is needed for correct diagnosis...

Juvenile papillomatosis of the larynx and trachea is a rare but well recognised condition, classically developing between the ages of 5 and 15 years but occasionally occurring in infancy. The tumours tend to recur before puberty but rarely do so afterwards. Malignant transformation is said not to complicate this condition.' This report describes a case of squamous carcinoma arising in a patient...

Sir, Confluent and reticulated papillomatosis (CRP) is a rare dermatosis of unknown origin characterized by hyperpigmented, confluent papules. The sites of predilection are the neck, inter-mammary area and abdomen (1). Rarely, CRP develops at the other sites, such as the knee, elbow, hand, and antecubital and popliteal fossae (2, 3). We describe two rare cases of CRP that developed at the elbow...

UNLABELLED The association of juvenile papillomatosis with carcinoma is proven, but very rare, as there exist several reported cases. CASE REPORT A 15-year-old girl with no family history of breast cancer presented with two masses in the left breast. The excisional biopsy on both lumps revealed juvenile fibroadenoma and juvenile papillomatosis epithelial proliferation multiple cystic expanded...