BACKGROUND The early determination of premalignant lesions of pancreas can prevent unnecessary excessive surgical procedures and can reduce morbidity and mortality. Pancreatic intraepithelial neoplasia-3 (PanIN-3) is a preinvasive form of adenocarcinoma (carcinoma in situ). PanINs have not taken place in the literature of radiology yet, it should be considered in differential diagnosis of pancr...

Pancreatic cancer, pancreatic ductal adenocarcinoma, is one of the most lethal malignancies, and researchers have therefore intensified efforts directed at its early detection and management. Early detection includes an effective screening program, as pancreatic cancer is known to evolve from precursor lesions, which can be identified using currently available diagnostic modalities. A recent mu...

Despite the remarkable advances in computed tomography and magnetic resonance imaging, their ability to differentiate pancreatic cystic lesions and to determine the presence of malignancy still remains uncertain.1 Although endoscopic ultrasound (EUS) provides detailed imaging of the pancreatic cystic lesions, the imaging features alone do not seem sufficient to differentiate benign from maligna...

Received 03 June 2013 Accepted 14 July 2013 Abstract This article reviews the current strategies and challenges of diagnosing pancreatic cystic lesions, and presents an overview of molecular tools that are available to enhance diagnostic accuracy. Specifically, we highlight the emergence of microRNAs (miRNAs) as diagnostic markers. miRNA signatures have been reported for both solid tissue and b...

Secondary pancreatic involvement can be seen up to 30% of advance staged non-Hodgkin’s lymphoma cases, but primary lymphomas constitute only 1% extranodal lymphomas. Furthermore, 0.2% the space-occupying lesions are lymphomas, which usually present as a mass in head pancreas with nonspecific symptoms. Therefore, should considered differential diagnosis solid lesions. Herein, we report two cases...

Vol. 20, No. 3 March 2013 JCOM 129 AbstrAct • Objective: To review the evaluation and management of pancreatic cystic lesions. • Methods: Review of the literature in the context of a clinical case. • Results: Pancreatic cysts are increasingly recognized due to the frequent use of abdominal imaging. Accurate characterization of these cysts is important not only to identify premalignant lesions t...