background: primary pancreatic lymphoma (ppl) is a rare condition and its differentiation from most commonly adenocarcinoma is very important because of different prognosis and treatment strategies. the aim of this study was presenting different aspects for differentiating ppl from pancreatic adenocarcinoma. materials andmethods: during 14 months, 5 patients who underwent endoscopic ultrasonogr...

PURPOSE The pathways of lymphatic metastases differ according to the tumor location in pancreatic cancer patients. However, it is unclear whether extended lymph node dissection (LND) is essential for all left-sided pancreatic cancer. The aim of this study is to evaluate the survival outcomes according to the extent of LND and tumor location in patients with left-sided pancreatic cancer. METHO...

Pancreatic cancer carries one of the worst prognoses in United States. It is fourth leading cause cancer-related death States and second after colorectal digestive system death. Early detection key to improving its prognosis. Surgical resection only curative treatment, but even margin-negative resection, 5-year survival rate still 30%. The following case presents a fascinating diagnosis pancrea...

abstract autoimmune pancreatitis (aip) is a rare disorder that may be present as common bile duct stricture. the patient was a seventy-year-old man with presentations as recurrent abdominal pain and jaundice, elevated billirobin (bil) and elevated alkaline phosphatase (alkp) in association with the presence of hetrogenesity of the pancreatic head and dilated intra and extra hepatic bile ducts i...

intraductal papillary mucinous neoplasms (ipmns) are rare pancreatic tumours, accounting for less of 1-2% of all neoplasms of the gland. main characteristics of ipmns are their favourable prognosis as these pre-malignant or frankly malignant lesions are usually slow-growing tumours and radical surgery is frequently possible. according with the localization of the lesions, three different entiti...

Pancreatic cancer belongs to the most aggressive cancer types, with an incidence rate equallig mortality rate. It is well‐known that type 2 diabetes is a significant risk factor for pancreatic cancer. Interestingly, several studies have shown that pancreatic cancer can also lead to type 2 diabetes, as part of the pancreatic cancer induced paraneoplastic syndrome. Multiple factors have been prop...

Early surgery is vital in the treatment of pancreatic cancer, which is often fatal. However, there is currently no useful noninvasive biomarker to screen for pancreatic cancer. Studies have documented that many salivary molecules can be used to detect systemic diseases. We investigated whether salivary miRNAs are useful biomarkers for detecting resectable pancreatic cancer. Using an Agilent mic...

Objective: In this article, we outline the important features of pancreatic cancer surgery in cases with visceral artery encasement.

Background. Both IL-9 and miR-200a are involved in the pathogenesis of cancers; however, the role of IL-9 in pancreatic cancer and the possible underlying mechanisms remain unknown. The aim of this study was to investigate the effect of IL-9 on pancreatic cancer cells and its interaction with miR-200a. Methods. Pancreatic cancer cells (PANC-1 and AsPC-1) were treated with IL-9 and the expressio...

Pancreatic cancer remains as one of the most aggressive types. In absence reliable biomarkers for its early detection and more effective therapeutic interventions, pancreatic is projected to become second leading cause death in Western world next decade. Therefore, it essential discover novel targets develop cancer-specific agents. To date, 45 monoclonal antibodies (mAbs) have been approved tre...