Cytochrome P450 BM3 (CYP102A1) from Bacillus megaterium is a self-sufficient monooxygenase that consists of a heme domain and FAD/FMN-containing reductase domain (BMR). In this report, the reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and 5-cyano-2,3-ditolyl tetrazolium chloride (CTC) by BMR was evaluated as a method for monitoring BMR activity. The electron tr...

The estimated energy requirement is important for adequate nutritional management in athletes. The energy requirement can be estimated from the basal metabolic rate (BMR). However, there is little data regarding the BMR of Japanese athletes. This study measured the BMR and body composition of 81 elite Japanese male athletes in different sports categories: endurance (E), strength, power and spri...

OBJECTIVE Basal metabolic rate (BMR) is the most important indicator of human metabolism and its abnormalities have been linked to undesirable health outcomes. Cigarette smoking associates with increased BMR in healthy individuals; it is also related with worse disease outcomes in patients with rheumatoid arthritis(RA), in whom BMR is high due to hypercatabolism caused by systemic inflammation....

The physiological mechanisms that determine basal metabolic rate (BMR) of endotherms have long been debated. This journal has recently presented a new model, based on biophysical principles of heat flux through the tissues of mammals, that attempts to explain the allometric relationship between BMR and body size. We offer a critique of the model and conclude that although the model may describe...

Basal rate of metabolism (BMR) and resting maternal rate of metabolism around peak lactation (RMR(L)) were measured in Crocidura russula, Mus domesticus and Microtus arvalis. These species have a moderate or high BMR relative to the scaling relationship of Kleiber. One goal of the study was to check whether females of these species show elevated rates of metabolism during lactation. A second go...

Substitution of threonine or serine for the evolutionary conserved intramembrane proline P347 of the Bacillus subtilis multidrug transporter Bmr significantly increases the toxin-effluxing activity of Bmr without affecting its abundance in the cell. In cocultivation experiments, we demonstrate that although the mutant T347 Bmr is advantageous to cells growing in the presence of a toxin, the wil...

BACKGROUND The total energy cost of pregnancy is largely due to an elevated basal metabolic rate (BMR). Large variations in the BMR response to pregnancy have been reported, but the factors associated with this variability are incompletely known. OBJECTIVE The objective was to identify factors associated with variability in the BMR response to pregnancy. DESIGN In 22 healthy women, BMR, bod...