BACKGROUND AND PURPOSE Acute stroke clinical trials are conducted primarily at academic medical centers. As a result, patients living in rural areas are excluded from participation, results may not be generalizable to nonacademic settings, and studies may be slow to recruit subjects. Telemedicine can provide rural patients with emergency neurovascular consultation. We sought to determine whethe...

A parallel genetic algorithm (GA) implemented on GPU clusters is proposed to solve the Uncapacitated Single Allocation p-Hub Median problem. The GA uses binary and integer encoding and genetic operators adapted to this problem. Our GA is improved by generated initial solution with hubs located at middle nodes. The obtained experimental results are compared with the best known solutions on all b...

In this paper, we address a new version of the Uncapacitated Single Allocation p-Hub Median Problem (USApHMP) in which transportation costs on each edge are given by piecewise constant cost functions. In the classical USApHMP, transportation costs are modelled as linear functions of the transport volume, where a fixed discount factor on hubhub connections is introduced to simulate economies of ...

In this paper we consider a capacitated single allocation p-hub median problem (CSApHMP) which is to determine the location of p hubs, the allocation of non-hub nodes to hubs in the logistics network. This problem is formulated as an integer programming model with the objective of minimizing the sum of total transportation cost and fixed cost of the selected p hubs. Since the CSApHMP is NP-hard...

New formulation and a branch-and-cut algorithm for the multiple allocation p-hub median problem Sergio García, Mercedes Landete and Alfredo Marín Septiembre 2011 ISSN 1576-7264 Depósito legal A-646-2000 Abstract This article deals with the uncapacitated multiple allocation phub median problem, where p facilities (hubs) must be located among n available sites in order to minimize the transportat...

The optimal locating of facilities has large effects on economic benefits, providing satisfactory service and levels of customer satisfaction. One of the new topics discussed in location problems is hub location and hub facilities are subject to unpredictable disruptions. This paper proposes a nonlinear integer model for reliable single allocation hub location problem that considers backup hub,...

Let $G$ be a bipartite graph. In this paper we consider the two kind of location problems namely $p$-center and $p$-median problems on bipartite graphs. The $p$-center and $p$-median problems asks to find a subset of vertices of cardinality $p$, so that respectively the maximum and sum of the distances from this set to all other vertices in $G$ is minimized. For each case we present some proper...

This paper proposes a new lower bounding procedure for the Uncapacitated Single Allocation p-Hub Median Problem based on Lagrangean relaxation. For solving the resulting Lagrangean subproblem, the given problem structure is exploited: it can be decomposed into smaller subproblems that can be solved efficiently by combinatorial algorithms. Our computational experiments for some benchmark instanc...

The Single Allocation Ordered Median Hub Location problem is a recent hub model introduced in [36] that provides a unifying analysis of a wide class of hub location models. In this paper, we deal with the capacitated version of this problem, presenting two formulations as well as some preprocessing phases for fixing variables. In addition, a strengthening of one of these formulations is also st...