Petroleum-derived monomers are the most common building blocks for ester-based thermosets. Bio-derived thermoset elastomers becoming viable alternatives to conventional Herein, we developed a biobased vitrimer-type using abundant and sustainable raspberry ketone as feedstock. We utilize create dynamic oxime chemistry crosslinked these through free radical polymerization with poly(ethylene glyco...

Reactivation of organophosphate (OP)-inhibited acetylcholinesterase (AChE) by oximes is the primary reason for their effectiveness in the treatment of OP poisoning. Reactivation is reported to accelerate by quaternary ligands such as decamethonium, which is devoid of nucleophilicity. The mechanism of this enhancement is not known. To better understand the acceleration phenomenon, we examined li...

hours the rotation was again taken: [ C ~ ] ~ D +77.2 * 5" (a% +1.75 * 0.1'; 1 = 2 dm.). Treatment of 17-Isopregnan-3( a)-ol-20-one with Hydrogen chloride.-In a manner similar to the above a solution of 44.7 mg. of 17-isopregnan-3(a)-ol-20-one made up to 5 ml. with 4.3% methanolic hydrogen chloride was refluxed for four hours and then the rotation was taken: [ a I s 1 ~ $75.6 * 5" ( C Y ~ ~ D $...

The semisynthetic antibiotic roxithromycin (RXM) exists in an (E)-configuration. Metabolites of RXM in the bile of four cholecystectomy patients with T-tube drainage and in the urine and plasma of four healthy volunteers after single oral doses of 150 mg of RXM were investigated. A total of 15 metabolites were found in bile, urine, and plasma by HPLC with ion trap mass spectrometric and electro...

The single-step construction of various densely oxygenated carboskeletons was achieved by radical-based twoand three-component coupling reactions of sugar derivatives, without the need for light or heat. Et3B/ O2-mediated decarbonylation readily converted a-alkoxyacyl tellurides to a-alkoxy carbon radicals, which intermolecularly added to glyoxylic oxime ether or enones to provide the two-compo...

In this enzyme immunoassay for ethynyl estradiol, a conjugate of the 3-(O-carboxymethyl)ether with horseradish peroxidase is used as the label and a conjugate of the 6-(O-carboxymethyl)oxime with bovine serum albumin as the immunogen. A solid-phase antibody procedure is used in separating antibody-bound and free steroid. The lower limit of sensitivity of the assay is 2 pg per assay tube. Interf...

The first radical intermediate in the thiourethane-mediated deoxygenation of an alcohol (Barton-McCombie reaction) can participate in an exo-hex-5-enyl- or exo-hept-6-enyl-type radical cyclization when a suitable radical acceptor (e.g., alpha,beta-unsaturated ester, oxime ether, or hydrazone) is appropriately placed. Carbohydrate-derived imidazolyl and triazolyl thiourethanes with such acceptor...