نتایج جستجو برای: oxidative stress inflammation

تعداد نتایج: 637033  

Journal: :iranian journal of basic medical sciences 0
farzaneh shakeri neurogeneeic inflammation research center, mashhad university of medical sciences, mashhad, iran department of physiology, school of medicine, mashhad university of medical sciences, mashhad, iran mohammad soukhtanloo department of biochemistry, school of medicine, mashhad university of medical sciences, mashhad, iran mohammad hossein boskabady neurogeneeic inflammation research center, mashhad university of medical sciences, mashhad, iran department of physiology, school of medicine, mashhad university of medical sciences, mashhad, iran

objective(s): the effects of curcuma longa (c. longa) and curcumin on total and differential wbc count and oxidant, antioxidant biomarkers, in rat model of asthma were evaluated. materials and methods: total and differential wbc count in the blood, no2, no3, mda, sod, cat and thiol levels in serum were examined in control, asthma, asthmatic rats treated with c. longa (0.75, 1.50, and 3.00 mg/ml...

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Journal: Journal of Fasting and Health 2020
Fatemeh Roudi, Golnaz Ranjbar, Mohsen Zakerian,

Oxidative stress after major surgeries is associated with the development of poor clinical outcomes including delayed wound healing and increase in Pediatric Intensive Care Unit (PICU) length of stay. Due to the growth and development phase in childhood, the change in the levels of oxidative stress and inflammation is of high importance in these patients. Notably, the acute metabolic stress whi...

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Journal: Journal of Biomedical Physics and Engineering 2016
A Rezaeyan A Salajegheh G H Haddadi M A Takhshid M Hosseinzadeh M Najafi, R Fardid,

Background: Oxidative stress plays an important role in the pathogenesis and progression of γ-irradiation-induced cellular damage, Lung is a radiosensitive organ and its damage is a dose-limiting factor in radiotherapy. The administration of dietary antioxidants has been suggested to protect against the succeeding tissue damage. The present study aimed to evaluate the radioprotective efficacy ...

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Journal: :The Journal of clinical investigation 2015
Santhosh Satapati Blanka Kucejova Joao A G Duarte Justin A Fletcher Lacy Reynolds Nishanth E Sunny Tianteng He L Arya Nair Kenneth A Livingston Xiaorong Fu Matthew E Merritt A Dean Sherry Craig R Malloy John M Shelton Jennifer Lambert Elizabeth J Parks Ian Corbin Mark A Magnuson Jeffrey D Browning Shawn C Burgess

Mitochondria are critical for respiration in all tissues; however, in liver, these organelles also accommodate high-capacity anaplerotic/cataplerotic pathways that are essential to gluconeogenesis and other biosynthetic activities. During nonalcoholic fatty liver disease (NAFLD), mitochondria also produce ROS that damage hepatocytes, trigger inflammation, and contribute to insulin resistance. H...

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Journal: :Microvascular research 2015
Daniela Sarmiento Ignacio Montorfano Oscar Cerda Mónica Cáceres Alvaro Becerra Claudio Cabello-Verrugio Alvaro A Elorza Claudia Riedel Pablo Tapia Luis A Velásquez Diego Varela Felipe Simon

A hallmark of severe inflammation is reactive oxygen species (ROS) overproduction induced by increased inflammatory mediators secretion. During systemic inflammation, inflammation mediators circulating in the bloodstream interact with endothelial cells (ECs) raising intracellular oxidative stress at the endothelial monolayer. Oxidative stress mediates several pathological functions, including a...

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2017
Guojun Wu Wenhong Zhou Junfeng Zhao Xiaohua Pan Yongjie Sun Hao Xu Peng Shi Chong Geng Ling Gao Xingsong Tian

The aim of this study was to investigate the protective effects of matrine on lipopolysaccharide (LPS)-induced inflammation and oxidative stress in vivo and in vitro. The results showed that matrine improved intestinal inflammatory status and oxidative balance and enhanced chemokine receptor 7 (CCR7) expression. In LPS-challenged mice and Caco-2 cells, matrine alleviated LPS-induced inflammatio...

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2014
Yu-Jin Hwang Jaewhan Song Haeng-Ran Kim Kyung-A Hwang

Oxidative stress and inflammation are common to many pathological conditions. Defense mechanisms protect cells from oxidative stress, but can become over-activated following injury and inflammation. NF-κB and Nrf2 transcription factors regulate proinflammatory and antioxidant gene expression, respectively. Studies have shown that many natural dietary compounds regulate NF-κB and Nrf2, preventin...

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2007
Rikard Åsgård Elisabet Rytter Samar Basu Lilianne Abramsson-Zetterberg Lennart Möller Bengt Vessby

Background: Patients with type 2 diabetes have increased levels of oxidative stress and inflammation. A high fruit and vegetable intake may be beneficial. Objective: To study whether fruit and vegetable intake and levels of plasma antioxidants relate to markers of oxidative stress and inflammation in a group of patients with type 2 diabetes. Further, to investigate whether plasma antioxidants a...

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Journal: :Oxidative Medicine and Cellular Longevity 2019

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2017
Alex Hall Andrea Troupin Berlin Londono-Renteria Tonya M. Colpitts

Dengue virus (DENV) is a mosquito-borne flavivirus that causes significant global human disease and mortality. One approach to develop treatments for DENV infection and the prevention of severe disease is through investigation of natural medicines. Inflammation plays both beneficial and harmful roles during DENV infection. Studies have proposed that the oxidative stress response may be one mech...

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