cognitive deficits have been observed in patients with multiple sclerosis (ms) because of hippocampal insults. oxidative stress plays a key role in the pathophysiology of ms. the aim of this study was to evaluate the effects of crocus sativus l., commonly known as saffron, on learning and memory loss and the induction of oxidative stress in the hippocampus of toxic models of ms. one week after ...

background homocysteine is a sulfur-containing amino acid which formed (mainly in the liver) during the metabolism of methionine. prior studies indicated the important role of hyperhomocysteinemia in pathogenesis and progression of alcoholic liver disease, liver steatosis and cirrhosis. one of the most important mechanisms by which homocysteine promote the development of hepatic injury is oxida...

as one of the most promising distributed generation (dg) sources, wind power technology has been widely developed in recent years. doubly fed induction generator (dfig) is currently employed as one of the most common topologies for wind turbine generators (wtgs). this generator operates as a synchronous/asynchronous hybrid generators. therefore, it is necessary to power engineers find understan...

A significant problem associated with the commercial acceptance of biodiesel is poor oxidative stability. This study investigates the effectiveness of various natural and synthetic antioxidants [a-tocopherol (a-T), butylated hydroxyanisole (BHA), butyl-4-methylphenol (BHT), tert-butylhydroquinone (TBHQ), 2, 5-di-tert-butylhydroquinone (DTBHQ), ionol BF200 (IB), propylgallate (PG), and pyrogallo...

Background: Elevated level of plasma homocysteine has been related to various diseases. Patients with hyperhomocysteinemia can develop hepatic steatosis and fibrosis. We hypothesized that oxidative stress induced by homocysteine might play an important role in pathogenesis of liver injury. Also, the cellular response designed to combat oxidative stress is primarily controlled by the transcripti...

Objective We examined genetic and dietary challenge on hippocampal oxidative damage. Mice expressing (ApoE+/+) or lacking apolipoprotein E (ApoE-/-) were maintained on a standard diet or a high fat /high cholesterol (challenge) diet for 11-31 weeks. Similar levels of oxidative species were observed for ApoE+/+ and -/- mice maintained on the basal diet. Method However, treatment of ApoE-/- hom...

Monoacylglycerols (MAG) containing polyunsaturated fatty acids (PUFA) have been synthesized by glycerolysis of anchovy oil using Lipozyme RM-IM in a solvent-free system. The experimental conditions, reaction temperature, substrate molar ratio (glycerol/triacylglycerol, Gly/TAG) and enzyme concentration were studied. A response surface methodology was employed to analyze the effect individual va...

this study investigated the fatty acids profile, oxidative stability indices, and bioactive compounds of virgin and processed olive oils (leccino and frantoio cultivars). results showed that fatty acid profile of the studied oils contained mostly oleic acid followed by palmitic and linoleic acid. acid values of virgin frantoio and processed leccino were 0.78 and 0.18 mg koh/g oil, with peroxide...

Introduction: Liver ischemia/reperfusion (IR) is a major clinical problem, which occurs during several conditions such as liver damage, trauma and transplantation. Recent studies indicate that IR-induced acute liver failure causes injuries of distant organs such as heart and lungs by systematic inflammatory responses. Therefore, in the present study, effects of hepatic IR induction were stud...