Series of polynuclear diorganotin(IV) complexes with di-halogenbenzohydroxamate ligands (substituents=2,4-Cl(2), 2,4-F(2), 3,4-F(2), 2,5-F(2), 2,6-F(2)), formulated as the polymeric [R(2)SnL](n)a (1:1) and the tetranuclear [R(4)Sn(2)(HL)(2)(L)](2)b (2:3) (HL=arylhydroxamate), were prepared and characterized by FT-IR, (1)H, (13)C, (119)Sn NMR spectroscopies, elemental analyses and melting point ...

The action of gut microflora on the metabolism of chloramphenicol (CP) was studied in germfree (GF) and conventional (CV) rats after administration of single oral doses of tritiated CP. There were similarities in the metabolic pathways of CP in the GF and CV animals, i.e., rapid absorption, hepatic glucuroconjugation, and biliary excretion of the CP conjugate. CP, CP-oxamic acid, CP-alcohol, an...

Mild digestion of isolated adipose tissue cells with Closfridium perjringens neuraminidase (10 to 20 mpg of purified enzyme per ml, 15 min at 37”) results in enhanced glucose transport by these cells. This effect appears to mimic closely the physiological effect of insulin on glucose transport by normal cells, and there is evidence to suggest that these two apparently different stimuli may affe...

The anodic oxidation of oxytetracycline was performed with success using as anode a boron-doped diamond electrode. The experiments were conducted in batch mode, using two different electrochemical cells: an up-flow cell, with recirculation, that was used to evaluate the influence of recirculation flow rate; and a stirred cell, used to determine the influence of the applied current density. Besi...

An alpha-sialoside linked to acrylamide by a short connector (5-acetamido-2-O-(N-acryloyl-8-amino-5-oxaoctyl)-2,6-anhydro-3,5-d ideoxy-D-galacto-alpha-nonulopyranosonoic acid, 1) was prepared. Compound 1 formed high molecular weight copolymers with acrylamide, derivatives of acrylamide, and/or vinylpyrrolidone upon photochemically-initiated free radical polymerization. Those copolymers for whic...