Smibert, Robert M. (Virginia Polytechnic Institute, Blacksburg, Va.). Nutrition of Vibrio fetus. J. Bacteriol. 85:394-398. 1963.-A chemically defined medium has been developed for the cultivation of both catalase-positive H(2)S-negative and catalase-positive H(2)S-positive strains of Vibrio fetus. A total of 87 strains of V. fetus, representing bovine, ovine, porcine, human, and chicken isolate...

The physiological role of endothelin-1 (ET-1) in regulation of vascular tone in the perinatal lung is controversial. Recent studies suggest that ET-1 contributes to high basal pulmonary vascular resistance in the normal fetus, but its role in the modulation of pulmonary vascular tone remains uncertain. We hypothesized that high ET-1 activity opposes the vasodilator response to some physiologica...

Ovine chlamydiosis, also known as enzootic abortion of ewes (EAE) or ovine enzootic abortion (OEA), is caused by the bacterium Chlamydophila abortus. Chlamydial abortion typically occurs in the last 2–3 weeks of pregnancy with the appearance of stillborn lambs and inflamed placentas. However, infection can also result in the delivery of full-term stillborn lambs or weak lambs that do not surviv...

Regulation of tone, blood pressure, and blood flow in the cerebral vasculature is of vital importance, particularly in the developing infant. We tested the hypothesis that, in addition to accretion of smooth muscle cells (SMCs) in cell layers with vessel thickening, significant changes in smooth muscle structure, as well as phenotype, extracellular matrix, and membrane proteins, in the media of...