نتایج جستجو برای: overexpression
تعداد نتایج: 75121 فیلتر نتایج به سال:
To explore the regulation and potential mechanism of long non-coding ribonucleic acid taurine upregulated gene 1 on apoptosis cell cycle osteoblasts is main purpose. The overexpression plasmid small interfering were used to regulate expression in osteoblasts. was detected by quantitative reverse transcription polymerase chain reaction effect flow cytometry, western blot analyses detect division...
Herbicides are the major tool for controlling large populations of yield depleting weeds. However, over-reliance on herbicides has resulted in weed adaptation and herbicide resistance. In recent years, early flowering species related to resistance is emerging, which may cause seed loss before crop harvest, creating a new problem non-chemical management. this study, homologue gene AGAMOUS sub-fa...
objective(s):n-myc downstream regulated gene 2 (ndrg2) is a candidate gene for tumor suppression. the expression of ndrg2 is down-regulated in several tumors including lung cancer. the aim of this study was to explore the effect of ndrg2 overexpression on invasion, migration, and enzymatic activity of matrix metalloproteinase-2 (mmp-2) and -9 (mmp-9) in human lung adenocarcinoma a549 cells. ma...
Background & Aims: Endometriosis is defined as the presence of tissue resembling endometrium outside the uterine cavity. Extensive remodeling existence in peritoneal mesothelium layer is necessary for adhesion, invasion, and proliferation of endometrial fragments, which is required the activation of matrix metalloproteinase (MMPs), as a normal menstrual cycle. MMPs are a family of zinc dependen...
Background:In tumoral cells, the HER-2/Neu is an oncogene and overexpression would result in further membranous proteins. The role of this gene is known in ling and breast cancers. This study was undertaken to determine the HER-2/Neu overexpression in gastrectomy samples in patients with gastric cancer and its association with tumor histopathology prognostic factors. M...
Introduction Introduction: Data from the CEO database shows microRNA (miR) -28-3p levels are elevated in diabetic patients. Nevertheless, role of miR-28-3p peripheral artery disease with diabetes have not been investigated. Material and methods The level miR-28-3p, CXXC5, CXXC-type zinc finger protein 5, CXXC5’s downstream molecules as well endothelial function were Dual luciferase analyses use...
Purpose: To investigate the effect of miR-493-5p in lipopolysaccharide (LPS) -induced ATDC5 chondrogenic cells.
 Methods: The MTT assay was used to determine viability LPS-induced cells. ENCORI (starbase.sysu.edu.cn/) predict target miR-493-5p. Quantitative reverse-transcription-polymerase chain reaction (qRT-PCR) expression controlled cells and treated with various combinations LPS, negat...
background: as the third most frequent cause of cancer death, breast cancer is a common disease worldwide. most of the patients are being diagnosed in the stage that conventional treatments are not effective, and invasion and metastases lead to death. therefore, identification of novel molecular markers to improve early diagnosis, prognosis and treatment of the breast cancer is a necessity. zin...
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