نتایج جستجو برای: overexpression

تعداد نتایج: 75121  

Journal: :Indian Journal of Pharmaceutical Sciences 2021

To explore the regulation and potential mechanism of long non-coding ribonucleic acid taurine upregulated gene 1 on apoptosis cell cycle osteoblasts is main purpose. The overexpression plasmid small interfering were used to regulate expression in osteoblasts. was detected by quantitative reverse transcription polymerase chain reaction effect flow cytometry, western blot analyses detect division...

Journal: :Functional Plant Biology 2021

Herbicides are the major tool for controlling large populations of yield depleting weeds. However, over-reliance on herbicides has resulted in weed adaptation and herbicide resistance. In recent years, early flowering species related to resistance is emerging, which may cause seed loss before crop harvest, creating a new problem non-chemical management. this study, homologue gene AGAMOUS sub-fa...

Journal: :iranian journal of basic medical sciences 0
seyed nooredin faraji diagnostic laboratory sciences and technology research center, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran zahra mojtahedi shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz, iran ghasem ghalamfarsa department of immunology, school of medicine, mashhad university of medical sciences, mashhad, iran mohammad ali takhshid diagnostic laboratory sciences and technology research center, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran

objective(s):n-myc downstream regulated gene 2 (ndrg2) is a candidate gene for tumor suppression. the expression of ndrg2 is down-regulated in several tumors including lung cancer. the aim of this study was to explore the effect of ndrg2 overexpression on invasion, migration, and enzymatic activity of matrix metalloproteinase-2 (mmp-2) and -9 (mmp-9) in human lung adenocarcinoma a549 cells.  ma...

خاکسار, فاطمه, موسی زاده, سپیده,

Background & Aims: Endometriosis is defined as the presence of tissue resembling endometrium outside the uterine cavity. Extensive remodeling existence in peritoneal mesothelium layer is necessary for adhesion, invasion, and proliferation of endometrial fragments, which is required the activation of matrix metalloproteinase (MMPs), as a normal menstrual cycle. MMPs are a family of zinc dependen...

Elham Jafari, Mohamad Javad Zahedi Mohammad Mahdi Hayatbakhsh Abbasi Nasrin Naghibzadeh Tahami Zarandi Sodaif Darvish Moghaddam

Background:In tumoral cells, the HER-2/Neu is an oncogene and overexpression would result in further membranous proteins. The role of this gene is known in ling and breast cancers. This study was undertaken to determine the HER-2/Neu overexpression in gastrectomy samples in patients with gastric cancer and its association with tumor histopathology prognostic factors. M...

Journal: :Archives of Medical Science 2023

Introduction Introduction: Data from the CEO database shows microRNA (miR) -28-3p levels are elevated in diabetic patients. Nevertheless, role of miR-28-3p peripheral artery disease with diabetes have not been investigated. Material and methods The level miR-28-3p, CXXC5, CXXC-type zinc finger protein 5, CXXC5’s downstream molecules as well endothelial function were Dual luciferase analyses use...

Journal: :Tropical Journal of Pharmaceutical Research 2023

Purpose: To investigate the effect of miR-493-5p in lipopolysaccharide (LPS) -induced ATDC5 chondrogenic cells.
 Methods: The MTT assay was used to determine viability LPS-induced cells. ENCORI (starbase.sysu.edu.cn/) predict target miR-493-5p. Quantitative reverse-transcription-polymerase chain reaction (qRT-PCR) expression controlled cells and treated with various combinations LPS, negat...

Journal: :Genome Biology 2001

Journal: :Hypertension 2003

Journal: :research in molecular medicine 0
mahboube ganji-arjenaki sku mojtaba emadi-baygi skum hossein teimori sku maryam moradi-chaleshtori skum valliollah mehrzad iums

background: as the third most frequent cause of cancer death, breast cancer is a common disease worldwide. most of the patients are being diagnosed in the stage that conventional treatments are not effective, and invasion and metastases lead to death. therefore, identification of novel molecular markers to improve early diagnosis, prognosis and treatment of the breast cancer is a necessity. zin...

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