In this investigation we describe our observations of the status of the aging ovary in mice with disruption of the receptor for FSH. Knockout mice at 3-5 months of age are acyclic and sterile, with very small, underdeveloped ovaries. Thus, they exhibit hypergonadotropic-hypogonadism with high levels of circulating FSH similar to the postmenopausal state in women. By 12 months more than 92% of t...

Primary ovarian choriocarcinoma arising from a germ cell is an extremely rare occurrence, especially in postmenopausal women, and the prognosis is poor. Non-gestational choriocarcinoma of the ovary (NGCO) accounts for 0.6% or less of all ovarian neoplasms. It is important to distinguish gestational choriocarcinomas of the ovary (GCO) from other carcinomas because of the poor prognosis of NGCO. ...

Involvement of the ovary by malignant lymphoma is well known as a late manifestation of disseminated disease. However, primary ovarian lymphoma (POL) is rare, accounting for 0.5 % of all non-Hodgkin’s lymphoma and 1.5 % of all ovarian neoplasms [1]. We present a case of ovarian non-Hodgkin’s lymphoma, manifesting like an advanced ovarian cancer, which was managed by surgery and chemotherapy (Fi...

Leiomyomas are benign neoplasms that can develop wherever smooth muscle is present. Primary leiomyomas of the ovary originate from smooth muscle cells of ovarian tissue and are rare, solitary tumors. Approximately 70 cases have been reported. They usually present in premenopausal women. The present case is a report of left ovarian leiomyoma in a postmenopausal woman.

Benign neoplasms of the ovary originating from epithelial tissue are common tumors in adult women. They are, however, rarely seen in children or adolescent girls. Here the authors present a case of an ovarian mucinous cystadenoma in a premenarchal girl. To our knowledge, there are only 5 other cases reported in the literature.

The Authors describe the clinical case of a seventeen-year-old girl who presented with abdominalgia, fever, nausea and vomiting. During surgery it proved necessary to remove not only the appendix but also a voluminous mucinous cystadenoma of the ovary. The authors take this observation as a starting point for a description of the pathophysiological and clinical findings of these neoplasms.

•We present a case of multiple mucinous metaplasia and neoplasia of cervix, endometrium, fallopian tube, ovary, and mesenterium with external urethral meatus neoplasm.•Immunohistochemistry showed almost same pattern in each neoplasms.•PCR-direct sequencing showed no existence of both KRAS and GNAS mutations.•This report suggests a possibility of synchronous mucinous metaplasia and neoplasia "be...

BACKGROUND AND OBJECTIVE The objective of this study was to explore whether fluorescence spectroscopy signatures differed between normal variations within the ovary, benign neoplasms, and ovarian cancer. STUDY DESIGN/MATERIALS AND METHODS Ovarian tissue fluorescence emission spectra were collected sequentially at 18 excitation wavelengths ranging from 330 to 500 nm from 11 patients undergoing...

BACKGROUND In the ovary, sarcomatoid carcinoma has been reported only as mural nodules in epithelial malignant or borderline serous or mucinous cystic neoplasms, and in teratomas. In this paper we report a rare case of a solid sarcomatoid carcinoma of the ovary, without accompanying component of giant cells, pleomorphic cells, or glandular and other epithelial structures. CASE PRESENTATION Th...

fine- needle (fna) cytology of ovary is a simple method for evaluation of ovarian masses. but there is controversy about its reliability in differentiating between benign and malignant neoplasms. to evaluate the efficiacy of fna cytology in the distinction between benign and malignant masses of ovary, we examined 55 fine needle aspirations from 55 women 14-74 years of age. the aspirations were ...