STUDY OBJECTIVE The aim was to investigate the association between reproductive, contraceptive, and menstrual factors and risk of benign ovarian tumours. DESIGN AND SETTING This was a case-control study carried out in six London Hospitals. An interviewer administered questionnaire was used. SUBJECTS 62 women with a benign epithelial ovarian neoplasm, 37 women with a functional ovarian cyst,...

Ovaries grafted into the spleens of gonadecto mized hosts are transformed into neoplasms in rats (2,14), mice (4, 7, 9, 11, 12), and rabbits (15). Al though there is a rapidly growing literature on the production of such ovarian neoplasms, very few reports have been concerned with their transplantability. Li and Gardner (11) stated that they made successful primary subpassages of several neopla...

Multiple primary neoplasms arising in the ovary and uterus were analyzed in 55 patients: 49 synchronous and 6, metachronous. When they occurred synchronously, 74.5% of the ovarian carcinomas and 93.6% of the uterine carcinomas were stage I lesions. The endometrial carcinomas were invariably well differentiated and superficial. It was the stage of the ovarian carcinomas that determined the progn...

Kras mutation is a common phenomenon in many human neoplasms. We aimed to assess the Kras mutational status along the histological continuum from normal ovaries to the development of benign, borderline and malignant ovarian mucinous neoplasms. We analyzed 41 cases of malignant, 10 cases of borderline, 7 cases of benign mucinous ovarian tumors and 7 cases of normal ovarian tissue. The prevalence...

The World Health Organization (WHO) classification of cystic pancreatic tumors defines mucinous cystic neoplasms as large, thick-walled, septated cysts with no communication with the main pancreatic duct, associated with the presence of ovarian-like stroma. Serous cystic neoplasms, on the contrary, present with a cuboidal or simple squamous epithelium and fibrous or hyalinized stroma without ov...

BACKGROUND AND PURPOSE Maspin is an inhibitor of serine proteinases with tumor suppressor activity that is down-regulated in breast and prostate cancer, but overexpressed in pancreatic carcinoma. However, there were very few published data regarding the role of maspin in ovarian carcinoma. The aim of the present study was to evaluate maspin expression in ovarian epithelial neoplasms and correla...

A retrospective study of 316 ovarian neoplasms which had frozen section evaluation between January 1, 1990 to December 31, 1995 was conducted to determine the accuracy of frozen section diagnosis of ovarian neoplasms. The frozen section results were compared with final diagnoses from paraffin sections. The frozen section diagnosis was accurate in 95.2% of all cases and inaccurate in 4.8%. The p...

Involvement of the ovary by malignant lymphoma is well known as a late manifestation of disseminated disease. However, primary ovarian lymphoma (POL) is rare, accounting for 0.5 % of all non-Hodgkin’s lymphoma and 1.5 % of all ovarian neoplasms [1]. We present a case of ovarian non-Hodgkin’s lymphoma, manifesting like an advanced ovarian cancer, which was managed by surgery and chemotherapy (Fi...