BACKGROUND To investigate the impact of previous ovarian surgery on ovarian reserve in patients with endometriosis. METHODS A total of 829 female patients were recruited. Their medical records were reviewed retrospectively. Patients who had diagnoses of endometriosis or endometrioma were defined as the endometriosis group, and those without endometriosis were as the control group. We further ...

BACKGROUND Endometriosis is a gynaecological disorder that affects 6-10 % of female population. It is characterized by the presence of endometrial tissue outside the uterus, most often in the pelvic peritoneum or ovaries. Recent studies have indicated that mesenchymal endometrial stem cells might get involved in endometriosis progression. Although germ line stem cells have been proved to exist ...

BACKGROUND Endometriosis is a benign and progressive disease with a high prevalence. Women with endometriosis, especially with atypical endometriosis, have a higher probability for developing ovarian cancer compared with women without endometriosis. The L1 cell adhesion molecule (L1CAM) is over expressed in ovarian and endometrial carcinomas and is associated with a bad prognosis. Here, we have...

Endometriosis is defined as presence of endometrial tissue outside of the uterus. It is a common disorder of women in reproductive age. It is estimated to occur in ten percent iof women in this age and even more in patients with infertility and pelvic pain. Endometriosis varies in appearance from a few minimal lesions to massive ovarian endometriotic cysts that distort the tubo-ovarian anatomy ...

Endometrioma is defined as an ovarian pseudocyst arising from growth of ectopic endometrial tissue, which progressively invaginates the ovarian cortex . Nearly17-44% of women with endometriosis also have endometriomas. Whereas detection of peritoneal endometriosis and adhesions typically requires laparoscopic assessment of the pelvis, endometriomas can be reliably diagnosed by transvaginal ultr...

BACKGROUND The aim was to evaluate whether patients with benign ovarian cysts, functional ovarian cysts, or endometriosis have an increased risk of developing gynecologic cancer. METHODS The Swedish Hospital Discharge Register was used to identify a cohort of women discharged from hospital with the diagnoses of ovarian cyst (n = 42217), functional ovarian cyst (n = 17998), or endometriosis (n...

The purpose of this study was two-fold, first to investigate the association between endometriosis and the risk of benign gynecologic tumors and, secondly, to evaluate the distribution of endometrioma and ovarian cysts in women with endometriosis. The medical and pathological reports of 1,000 women with endometriosis were retrospectively reviewed. The incidence of ovarian cysts, uterine leiomyo...

Accumulating evidence suggests that advanced (moderate/severe) endometriosis negatively affects female fecundity, whereas the influence of early (minimal/mild) endometriosis on human reproduction remains unclear. Recent studies showed that the presence of the early pelvic endometriosis lesions deteriorates the ovarian reserve, luteal function, and fertilization rate in infertile women undergoin...

BACKGROUND Endometriosis is associated with inflammatory autoimmune reactions; however, aetiopathogenesis of the disease is still poorly understood. While autoimmune disorders are often associated with particular HLA alleles, the possible involvement of HLA in the aetiopathogenesis of endometriosis is still a subject of controversy. The aim of the study was to examine the distribution of HLA-DR...

Endometriosis is defined by the presence of tissue implants resembling endometrial glands outside of the uterus, at ectopic sites, frequently on the ovarian surface. The ectopic lesions are often invasive, resistant to therapy, and may predispose to endometrioid and clear cell ovarian tumors. The complex mechanisms leading to chronic endometriosis are mediated partly by impaired immune surveill...