Ovarian cancer (OV) is the most common and lethal gynecological tumor with a poor prognosis for women; however, the regulatory roles of the long non-coding RNAs (lncRNAs) in ovarian malignant progression are insufficiently understood. Here, we investigated the expression patterns of lncRNAs and mRNAs in the high-throughput molecular profiles of 399 OV patients and constructed a functional lncRN...

Metal tellurides attract recent attention because of their promising applications as effective catalysts for the oxygen evolution reaction (OER). However, inappropriate adsorption energy between OER intermediates and telluride leads to an unsatisfactory electrocatalytic intrinsic activity. Herein, we adopt a unique in-situ cathodic electrochemical activation process facilitate surface self-reco...

Through a two-step solvothermal method, different molar ratios of BiPO4 were grown in situ on the surface oxygen-vacancy-rich BiOBr (Ov-BiOBr), successfully constructing BiPO4/Ov-BiOBr heterojunction composite material. By novel type I high-low junction between semiconductor and Ov-BiOBr, stronger oxidative holes or reductive electrons retained, thereby improving redox performance photocatalyst...

OBJECTIVE To demonstrate whether leptin modulates reproduction by a direct effect within the ovary. DESIGN Animal model. SETTING National Key Laboratory of Infertility. ANIMAL(S) Adult female db/db mice. INTERVENTION(S) Adult littermate wild-type (WT) and diabetic (db) leptin receptor (LR) mutant female mice were matched for the allograft of the ovary to construct new genotypic models, ...

Ovarian cancer (OV) ranks fifth in cancer deaths among women, yet there remain few informative biomarkers for this disease. Microsatellites are repetitive genomic regions which we hypothesize could be a source of novel biomarkers for OV and have traditionally been under-appreciated relative to Single Nucleotide Polymorphisms (SNPs). In this study, we explore microsatellite variation as a potent...

BACKGROUND In some regions in Africa, elimination of onchocerciasis may be possible with mass drug administration, although there is concern based on several factors that onchocerciasis cannot be eliminated solely through this approach. A vaccine against Onchocerca volvulus would provide a critical tool for the ultimate elimination of this infection. Previous studies have demonstrated that immu...

This data paper contains information about the in vivo model for peritoneal implants used in the paper "Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells" (De Vlieghere et al., 2015) [1]. A double in vivo selection of SK-OV-3 Luc human ovarian cancer cell line was used to create SK-OV-3 Luc IP1 and SK-OV-3 Luc IP2 cell lin...

Objectives: Little is currently known on how human ocular volume (OV) relates to body size or composition across adult men and women. This gap was filled in an exploratory study on the path to developing anthropological and physiological models by measuring OV in young healthy adults and related brain, head, and body mass along with major body components. Methods: Thirty-six men and 44 women, a...