INTRODUCTION Osteoporosis, the most common metabolic disorder, can eventually lead to fragility fractures. Of all osteoporotic fractures, vertebral wedge fractures are the most common. They are associated with pain, a decrease in quality of life, and a change in spinal alignment. The changed spinal alignment increases the chance of subsequent fractures: a wedge fracture changes the loading dire...

Osteoporotic-associated vertebral compression fractures are a major public health concern, dwarfing even hip fractures in incidence in the United States. These fractures carry a significant morbidity and mortality burden and also represent a major growing source of consumption of scarce heath resources. Percutaneous vertebroplasty remains a commonly used and safe technique for the symptomatic t...

Osteoporotic fractures have become one of the most prevalent trauma conditions seen daily in clinical practice [1]. They are also known as ‘fragi lity fractures’ and they are defined as those occurring after a low-energy trauma, traditionally interpreted as a fall from a standing height or less [2]. Contributing factors are the susceptibility to falls and underlying osteoporosis, which is chara...

Osteoporotic fractures are a major cause of morbidity and mortality in ageing populations. Osteoporosis, defined as low bone mineral density (BMD) and associated fractures, have significant genetic components that are largely unknown. Linkage analysis in a large number of extended osteoporosis families in Iceland, using a phenotype that combines osteoporotic fractures and BMD measurements, show...

INTRODUCTION Pertrochanteric fractures after low-energy trauma are common among osteoporotic patients. Although the use of intramedullary devices to treat such fractures is becoming increasingly popular, there is a paucity of data comparing the outcomes of the use of short cephalomedullary nails (SCN) with the use of long cephalomedullary nails (LCN). This study aimed to compare the outcomes of...

While current use of menopausal hormone therapy (MHT) reduces the risk of osteoporotic fractures, epidemiologic studies suggest that protection wears off rapidly after discontinuation of treatment. The authors identified 5,589 first osteoporotic fractures (2,235 major osteoporotic fractures) among 70,182 postmenopausal women from the French E3N cohort (1992-2008) and used Cox multivariate propo...

With an aging population worldwide, the frequency of osteoporotic fractures is increasing. Therefore, biological methods to enhance the internal fixation of osteoporotic fractures becomes more important to reduce the societal burden of care. The purposes of this study were to evaluate the role of platelet-rich plasma (PRP) in the treatment of osteoporotic fractures and to clarify the best conce...

OBJECTIVE To evaluate the performance of the QFractureScores for predicting the 10 year risk of osteoporotic and hip fractures in an independent UK cohort of patients from general practice records. DESIGN Prospective cohort study. SETTING 364 UK general practices contributing to The Health Improvement Network (THIN) database. PARTICIPANTS 2.2 million adults registered with a general pract...

BACKGROUND Associations between metabolic syndrome (MetS) and osteoporotic fracture have been reported. However, the epidemiological studies are not conclusive. The objective of the study was to determine whether metabolic syndrome associates with osteoporotic fracture. METHODS This was a cross-sectional study of 9930 Chinese adults aged 40 year or older in the Chongming District, Shanghai, C...

Objective: Correlation of osteoporosis (OP) with type 2diabetes mellitus (DM) , is not as clear as type 1 DM. The purpose of this study was to compare the frequency of OP and osteoporotic fractures in post- menopausal women with and without type 2 DM in Sari, Iran. Materials and Methods: Eighty post-menopausal women with type 2 DM and 80 non-diabetic controls enrolled in this study. Bone mine...