The aim of this investigation was to prepare, characterize and optimize the aceclofenac proniosomes using central composite design and carry out stability studies. Three independent variables selected were molar ratio of drug to lipid (X1), surfactant loading (X2) and volume of hydration (X3). Based on central composite design, 16 batches of proniosomes were prepared by slurry method and evalua...

The aim of this investigation was to prepare, characterize and optimize the aceclofenac proniosomes using central composite design and carry out stability studies. Three independent variables selected were molar ratio of drug to lipid (X1), surfactant loading (X2) and volume of hydration (X3). Based on central composite design, 16 batches of proniosomes were prepared by slurry method and evalua...

In this article, we study the numerical approximation of the solution of the Cauchy problem for a multidimensional linear parabolic PDE of second order, with unbounded time and space-dependent coefficients. The PDE free term and the initial data are also allowed to grow. Under the assumption that the PDE does not degenerate, using the L2 theory of solvability in weighted Sobolev spaces, the PDE...

The population density equation (PDE) has generated considerable interest, recently. The PDE allows e.cient simulation of populations with a large number of neurons. We apply the PDE to an existing model of delay activity, which produces stationary 1ring rates for delay assemblies. In order to observe transient phenomena, we apply the PDE to this model. Here we present the preliminary results. ...

Using the theory of the symmetry groups for PDEs of order two ([7], [17], [20]), one finds the symmetry group G associated to Ţiţeica surfaces PDE. One proves that Monge-Ampère-Ţiţeica PDE which is invariant with respect to G, where G is the maximal solvable subgroup of the symmetry group G, is just the PDE of Ţiţeica surfaces. One studies the inverse problem and one shows that the Ţiţeica surf...