BACKGROUND The purpose of this prospective, randomized study was to compare the safety and efficacy of oral versus i.v. midazolam in providing sedation for pediatric upper gastrointestinal (GI) endoscopy. METHODS Sixty-one children (age <16 years) scheduled for upper GI endoscopy were studied. Patients were randomly assigned to receive oral or i.v. midazolam. Measurements were made and compar...

BACKGROUND Pediatric dentists face challenges when young patients require a mesiodens extraction. General anesthesia may be a burden to the child as well as the parent due to dental fears and costs. The aim of this study was to evaluate oral and intravenous sedation in the outpatient setting as a safe and effective means of managing patients who require a mesiodens extraction. METHODS Records...

PURPOSE In this study, we retrospectively investigated case reports with and without midazolam administration via oral, intranasal and rectal before cystometry procedure. We aimed to compare the data to evaluate the effects of sedation before cystometry on the pediatric patients and parents' satisfaction. METHODS A total of 124 ASA I-II pediatric cases aged 5-14 years were retrospectively inv...

INTRODUCTION The use of diagnostic auditory brainstem response testing under sedation is currently the "gold standard" in infants and young children who are not developmentally capable of completing the test. OBJECTIVE The aim of the study is to compare a propofol-ketamine regimen to an oral chloral hydrate regimen for sedating children undergoing auditory brainstem response testing. METHOD...

background: the goal of this investigation was to compare the behavioral and physiological effects of three sedative drug regimens: oral meperidine (om), submucosal meperidine (sm) and oral midazolam (m) in healthy pediatric patients. materials and methods: this study sample consisted of thirty children aged 24-72 months (mean = 41.1) exhibiting definitely negative behavior. three sedative regi...

Topical anesthesia for flexible bronchoscopy can be achieved in several ways like administration of an anesthetic agents by injecting through cricothyroid membrane,by giving drug lignocaine through Nebulization, 3}administering the drug through oral spray. Nebulization of lidocaine can achieve very satisfying anesthesia comparable to oral spraying with significant low plasma levels of the drug....

PURPOSE To evaluate the safety and usefulness of the use of oral sedation with midazolam (15 mg) in patients submitted to blepharoplasty. METHODS Randomized double-blind prospective study of 42 patients (surgical risk ASA I and II) divided into three groups of 14 patients each: Group M (midazolam 15 mg), group P (placebo) and group SM (no medication). All patients were evaluated according to ...

PURPOSE Our goal was to report on the incidence of sedation failures in our outpatient oral surgery clinic. Sedation failure is the inability to complete a procedure under intravenous sedation. There is very little in the oral surgery literature on this subject. MATERIALS AND METHODS Proper Institutional Review Board approval was obtained from the appropriate governing body for this project. ...

The efficacies and ease of administration of four oral preanesthetic sedation protocols were compared in 18 adult, male rhesus macaques (Macaca mulatta) to achieve heavy sedation and alleviate anxiety, agitation, and potential trauma associated with remote anesthesia induction. The macaques, with average age and weight of 10 yr and 12.5 kg, respectively, were randomly assigned to one of four gr...

In a prospective, double-blind, controlled study the efficacy of clonidine was assessed in children, with respect to sedation, intubation response, and recovery. Fifty children, aged 4-12 years, undergoing general anesthesia were studied. Twenty-five children (group I) received oral diazepam) 0.2 mg/kg and another 25 children (group II) received oral clonidine 3 micrograms/kg, 90-120 minutes be...