PURPOSE/OBJECTIVES To review the research studies on the current treatments for radiation therapy-(RT-) induced mucositis in patients with head and neck cancer. DATA SOURCES MEDLINE search of the literature from 1966-2001. DATA SYNTHESIS Four types of agents (i.e., antimicrobial, coating, anti-inflammatory, and cytokine-like agents) have been evaluated for the management of RT-induced oral ...

PURPOSE/OBJECTIVES To describe the current knowledge about the pathogenesis of oral mucositis associated with cancer therapy and oral mucositis. DATA SOURCES Published research and literature review articles, books, and posters of findings that have been selected for presentation at research conferences. DATA SYNTHESIS Aggressive cancer treatment yields gains in cure or sustained control bu...

Of the toxicities associated with conventional forms of treatment for head and neck cancers, probably none has such a consistent legacy as oral mucositis.1 Despite the fact that mucosal injury was noted as far back as Marie Curie's first forays into therapeutic radiation, an effective intervention has yet to be developed. In addition to its historic link to radiation, new therapeutic strategies...

One of the most common complications of cancer chemotherapy is oral mucositis. This study evaluates the therapeutic effects of honey with the focus on grade III and IV oral mucositis, reduction of bacterial and fungal infections, duration of episodes of oral mucositis, and body weight in pediatric leukemic patients undergoing chemo/radiotherapy. This is an open labeled randomized controlled stu...

This review aims to analyse the potency of Aloe vera for Oral Mucositis (OM) therapy. Articles searched using keywords “Oral Mucositis” AND “Aloe vera”, conducted through PubMed, ScienceDirect, and Cochrane Library databases, adapted PICO (Population, Intervention, Comparison, Outcome) framework. The inclusion criteria articles were: Randomized Controlled Trial (RCT) study design; in English; f...

radiotherapy in the head and neck region and chemotherapy might give rise to oral mucositis which is a severe and painful inflammation. there is no known definite cure for mucositis. a number of studies have attempted to evaluate the effect of low-power laser on radiotherapy- and chemotherapy-induced mucositis. the present study was undertaken to evaluate the effect of low-power laser on the pr...

ackground. Oral mucositis is a common complication of some malignancies treatment, causing therapeutic modifications due to patient’s debilitation, which often interferes with the prognosis of the disease. Many attempts have been made to find an optimal treatment or preventive method to minimize the severity of oral mucositis. Several studies have shown good results with the use of low-energy l...

BACKGROUND The purpose of this study was to assess predictors of mucositis in oropharyngeal and oral cavity cancer after definitive or adjuvant volumetric modulated arc radiotherapy (VMAT) +/- chemotherapy. METHODS Fifty patients were evaluated. Statistical analysis was performed for the following parameters as potential predictors of mucositis ≥ G2: total oral mucosa and oral mucosa minus ta...

Background: One of the symptoms of mucositis caused by chemotherapy is pain. Mucositis management is initiated by assessment of oral hygiene and management of pain. Many uses have been mentioned for Satureja hortensis in traditional medicine. The study was carried out with the aim of determining the effect of Satureja hortensis extract mucoadhesive gel of 1% on severity of mucositis-induced pai...

objectives the aim of this study was to investigate the effects of local cryotherapy on the intensity of chemotherapy-induced oral mucositis in autologous bone marrow transplantation patients. patients and methods in this single, blinded, randomized clinical trial, 29 patients undergoing stem cell transplantation in iran were selected by convenience sampling, and randomly allocated to control (...