BACKGROUND The purpose of this study was to assess predictors of mucositis in oropharyngeal and oral cavity cancer after definitive or adjuvant volumetric modulated arc radiotherapy (VMAT) +/- chemotherapy. METHODS Fifty patients were evaluated. Statistical analysis was performed for the following parameters as potential predictors of mucositis ≥ G2: total oral mucosa and oral mucosa minus ta...

background: bone marrow mesenchymal stem cells (bmscs) are the key to regenerative wound healing. mscs have spatial memory and respond to local environment. the goal of this study was to evaluate the use of systemic and intralesional transplantation of bmscs for regeneration of oral mucosa in an in vivo dog model. materials and methods: transplantation of undifferentiated green fluorescent prot...

The oral mucosa is a critical barrier tissue that harbors a series of distinct immune cell subsets. Immune surveillance in the oral mucosa is important for both local and systemic immunity because the oral cavity is a heavily utilized route of pathogen entry and also serves as site of pathogen propagation. Nonetheless, composition and phenotype of the lymphocyte pool in the oral mucosa have rem...

background: candidal colonization in complete denture wearers is a commonly encountered condition that worsens in the presence of untreated diabetes mellitus. the aim of this study was to evaluate the correlation between oral candidiasis in denture‑bearing mucosa and elevated blood glucose levels in complete denture wearers and to evaluate the effect of oral hypoglycemic drug therapy in control...

OBJECTIVE Epithelial wound repair assures the recovery of the epithelial barrier after wounding. During wound healing epithelial cells migrate to cover the wound surface. For healing of skin wounds the skin keratinocytes can be replaced by oral mucosa epithelial cells grown in vitro. The presented experiments were carried out in order to compare the proliferation, morphology, and migration betw...

HIGHLIGHTS Phenolic derivatives exert a genotoxic effect on the oral mucosa. The use of personal protective equipment and/or exhaust laminar flow hood reduces effects. Long-term exposure to agents can be measured by mucosa samples.

The aim of this study was to determine histological changes in rats’ oral mucosa at induced postmenopausal oestrogen decrease and after administration of raloxifene and 17β-oestradiol. Wistar female rats were ovariectomized and divided into experimental groups; basal – after ovariectomy without drugs BOV, taking raloxifene RA and oestradiol – OVH (10 rats per group). Additionally, 10 rats witho...