Objectives: To assess the effectiveness, safety and acceptability of intracervical foley catheter and vaginal misoprostol versus vaginal misoprostol for termination of second trimester pregnancy. Methods: This clinical study was conducted on 200 pregnant patients intended for termination of pregnancy between 13-24 gestational weeks for any indication. Enrolled women were equally allocated into ...

OBJECTIVE To compare the efficacy and safety of oral versus vaginal administration of misoprostol for second trimester pregnancy termination. STUDY DESIGN Interventional, quasi experimental study. PLACE AND DURATION OF STUDY The Department of Obstetrics and Gynaecology Unit-II, Fatima Jinnah Medical College/Sir Ganga Ram Hospital, Lahore, from August, 2003 to October, 2004. METHODOLOGY Si...

At times, despite an unripe cervix, induction of labor may be needed. In these cases, a safe and suitable method should be considered for cervical ripening and pregnancy termination. The aim of this study is the comparison of vaginal misoprostol with Foley catheter for cervical ripening and induction of labor. This randomized clinical trial was performed on 108 pregnant women who had referred t...

BACKGROUND Mifepristone, followed 48 hours later by administration of misoprostol, is a well-established regimen for medical termination of pregnancy (TOP). Although this regimen is effective, its inflexibility may limit its provision in an outpatient service. OBJECTIVE To confirm that misoprostol administration is effective whether administered 24, 48 or 72 hours after oral mifepristone. D...

OBJECTIVE To compare the efficacy of the vaginal and sublingual administration of the synthetic prostaglandin misoprostol with the currently used oral administration route in second-trimester medical abortion. METHODS This was a prospective randomized trial of medical abortion with misoprostol after mifepristone priming at 14-24 weeks of gestation. From 2009 to 2013, recruited women received ...

Misoprostol, a prostaglandin E1 analogue, is first used to prevent peptic ulcers. The FDA-approved indication in the product labelling for prevention and treatment of intestinal ulcer disease caused by use nonsteroidal anti-inflammatory medications. main advantages misoprostol include it's reasonably priced, compared other prostaglandins, it has modest effects on smooth muscle heart bronchial t...

Objective: Retrospective analysis and evaluating reliability and efficiency of misoprostol in 87 cases having pregnancy termination by using vaginal misoprostol between 12 and 35 weeks’ gestation. Methods: The present study was conducted at Celal Bayar University, Gynecology and Obstetrics Clinic, Perinatology unit between January 2006 and November 2008. A total of 87 cases at more than 12 week...

Overview and Aims: To determine the efficacy of vaginal misoprostol as standard protocol in second trimester medical termination of pregnancy. Study Design: Retrospective cohort analysis. Population: Women who underwent pregnancy termination between 12 and 24 weeks for medical reasons, over a 5-year period. Methods: A standard 400mcg misoprostol dosage was given intravaginally every 6 hours unt...