Oral leukoplakia is a common potentially malignant oral lesion. Most scholars consider that its cancerization follows a multistep process of gradual progression. If surveillance and assessment could be performed at earlier stages to assess the risk of cancerization, the probability of malignancy would obviously be reduced. In this paper, we report on a patient with cancerous oral leukoplakia in...

OBJECTIVE To measure the lipid peroxidation and endogenous antioxidant enzyme status in oral carcinoma and the protective role of exogenous antioxidants. MATERIAL AND METHODS 20 new cases of histologically proven oral squamous cell carcinoma, 20 of leukoplakia and 20 age and sex matched healthy conrols were included. Intra oral pH of patients and controlled were measured by quantitative litmu...

The word "leukoplakia" literally means a white patch. Over the years, there has been a lot of confusion regarding the usage of this term, as there are numerous specific oral white lesions that must have been referred to as leukoplakia. WHO Collaborative Reference Centre for Oral Precancerous Lesion 1 defined leukoplakia as "A white patch, after clinical and laboratory investigations, cannot be ...

OBJECTIVES to report the immunoexpression of metallothionein in oral leukoplakia and to correlate with histological grade and clinical localization. Leukoplakia is the most common potentially malignant lesion of the oral cavity. As the histological study of oral leukoplakia can not predict precisely the malignant transformation of this lesion, and metallothionein is a protein that has been asso...

background and aims. many oral squamous cell carcinomas develop from potentially malignant disorders (pmds) which include a variety of lesions and conditions characterized by an increased risk for malignant transformation. this study evaluated the quantitative expression of egfr in normal oral mucosa, oral leukoplakia and oral submucous fibrosis to predict the malignant risk in compliance with ...

Background: Oral cancer is one of the most significant reasons death in India. The quantitative and qualitative assessment AgNORs parameters has been used oncology for both diagnostic prognostic objectives. number distribution AgNOR nucleus (configuration) were helpful detecting predicting prognosis various neoplasias. Aim: To assess biologic aggressiveness leukoplakia, oral submucous fibrosis ...

Management of potentially malignant disorders such as leukoplakia depends onearly interception &prevention of malignant transformationwhich includes several factors such as age of patients, systemic factors ,history of habits ,size & site of lesion ,its type & clinical features ,natural history & histopathological features .This is achieved by habit counseling for tobacco dependence and use of ...

BACKGROUND Oral cancer is associated initially by the presence of pre-malignant lesions or pre-malignant conditions. Oral Leukoplakia is one of the best-known pre-malignant lesions in the oral cavity that have the highest rate of malignant transformation. Numerous studies have shown an altered lipid profile in various cancers including head and neck cancers. An inverse relationship between plas...

OBJECTIVE To document the prevalence, age and gender distribution of oral lesions in HIV infected adults and the influence of highly active antiretroviral therapy and correlate them to the immune status of the patients. MATERIALS AND METHODS Oral lesions were diagnosed by a detailed physical examination by trained and calibrated examiners according to the case definitions established by the O...