Background: Oral squamous cell carcinoma is the sixth most common malignancy in the world today.  ING1b/p33 is a newly-discovered tumor suppressor which enhances p53 activity. Transfer of p33 protein from nucleus to cytoplasmic compartment has been previously reported in leukemias. The objective of this study was to determine the correlation between p33ing1b cytoplasmic transfer and lymph node ...

Introduction: Oral verrucous carcinoma (OVC) is a rare malignancy of the oral cavity that was first described by Ackerman. This tumor is a well-differentiated low-grade, slow growing cancer that is locally invasive without metastasis. Ameloblastoma is one of the most common odontogenic tumors, which originates from the odontogenic epithelium. Verrucous carcinoma along with central ambloblastoma...

INTRODUCTION Oral verrucous carcinoma is a special form of well-differentiated squamous cell carcinoma which possesses specific clinical, morphologic and cytokinetic features that differ from other types of oral cancers and hence diagnosis requires immense experience in histopathology. Hence it is certainly important to distinguish such a lesion from other oral tumors as treatment strategies va...

myiasis is the condition of infestation of the body by fl y larvae (maggots). the deposited eggs develop into larvae, which penetrate deep structures causing adjacent tissue destruction. it is an uncommon clinical condition, being more frequent in tropical countries and hot climate regions, and associated with poor hygiene, suppurative oral lesions, alcoholism and senility. the diagnosis of myi...

background: oral squamous cell carcinoma is the sixth most common malignancy in the world today.  ing1b/p33 is a newly-discovered tumor suppressor which enhances p53 activity. transfer of p33 protein from nucleus to cytoplasmic compartment has been previously reported in leukemias. the objective of this study was to determine the correlation between p33ing1b cytoplasmic transfer and lymph node ...

Background: Oral cancer is among the 10 most common cancers worldwide with an increasing global incidence. Compromised antioxidant defense system plays a role in occurrence of cancer. This study evaluated the salivary antioxidant level of oral cancer patients compared to a control group. Patients and Methods: This case-control study was conducted on 22 oral squamous cell carcinoma patients pre...

the role of oxygen free radicals in the initiation, promotion and progression of carcinogenesis and the protective role of anti-oxidant defenses has been the subject of much speculation in the recent past with conflicting reports in the literature. in recent years, increasing experimental and clinical data have provided compelling evidence for the involvement of oxidative stress in a large numb...

Introduction: As a result of aging process, oral mucosa becomes susceptible to oral diseases. Having knowledge about prevalence and distribution of geriatric oral diseases is essential for prevention and treatment planning. This study aimed to evaluate the prevalence of geriatric patients’ oral biopsies in specimens obtained in medical centers of Zahedan University of Medical Sciences. Methods:...

β-Catenin acts as a structural protein at cell-cell adherens junctions and as a transcription activator mediating Wnt signal transduction. Altered β-catenin expression has been associated with loss of cell differentiation and acquisition of an invasive phenotype. In the present study, β-catenin expression was compared immunohistochemically between oral squamous cell carcinoma (30 cases) and ver...