Background and Aim: The aim of this study was to conduct in vitro and in vivo studies for the evaluation of antimicrobial potential of four Nigerian indigenous chewing sticks and to compare the oral effects of the popular Nigerian chewing sticks with toothpastes and other teeth-cleansing agents on a total of 21 and 17 oral bacterial strains isolated from children and adult dental caries respect...

The female genital tract has a complex microbial flora which varies with site, age of the patient, and hormonal background. Likewise, the quality and quantity of cervical and vaginal secretions vary with many factors including age, phase of the menstrual cycle, use of oral contraceptive, pregnancy, and presence of an intrauterine contraceptive device. Vaginal discharge may arise from the vagina...

P diseases are recognized as bacterial infections, and some forms are associated with specific organisms, such as Actinobacillus actinomycetemcomitans in juvenile periodontitis, and Bacteroides gingivalis and others in adult periodontitis. The source of the periodontal organisms, whether they are part of the indigenous or resident flora and overgrow to become opportunistic oral pathogens, or wh...

BACKGROUND Although the etiology of idiopathic ulcerative colitis (UC) remains poorly understood, the intestinal flora is suspected to play an important role. Specific, consistent abnormalities in flora composition peculiar to UC have not yet been described, however Clostridium difficile colitis has been cured by the infusion of human fecal flora into the colon. This approach may also be applic...

Introduction: However human oral cavity consist a mass of microorganisms, some alteration such as application the complete removable denture with poor oral hygiene in edentulous patients may cause overgrowth of several opportunistic microorganisms resulted denture stomatitis. The aim of present study was to compare the dominant oral micro-flora between edentulous denture users with dentate elde...

BACKGROUND For periodontal treatment, the full mouth disinfection approach suggests disinfection of oral soft tissues, such as tongue and tonsils concomitant to scaling and root planning since patients might benefit from treatment of these oral niches either. Periodontopathogenes in tonsillar tissue support this hypothesis. This prospective controlled clinical study investigated the change in t...

There is an increasingly growing interest world-wide for the genomics, transcriptomics and proteomics of saliva and the oral cavity, since they provide a non-invasive source of unprecedently rich genetic information. The complexity of oral systems biology goes much beyond the human genome, transcriptome and proteome revealed by oral mucosal cells, gingival crevicular fluid, and saliva, and incl...

Assessing bacterial flora composition appears to be of increasing importance to fields as diverse as physiology, development, medicine, epidemiology, the environment, and the food industry. We report here the development and validation of an original microarray strategy that allows analysis of the phylogenic composition of complex bacterial mixtures. The microarray contains approximately 9,500 ...

Actinomycosis is a rare anaerobic bacterial infection typically caused by Actinomyces israelii. Although part of normal flora in the oral cavity, and respiratory and digestive tracts, A israelii can give rise to pathologic infections most commonly reported in the oral cavity from odontogenic causes. We present a rare case of invasive actinomycosis presenting with extensive midface destruction i...

The pharmacokinetics of ciprofloxacin and its effect on the oropharyngeal bacterial flora were examined in 21 ill patients being treated for methicillin-resistant Staphylococcus aureus infections or colonization or both. Oral ciprofloxacin (750 mg twice a day) produced peak and trough concentrations in serum of 2.56 +/- 1.80 and 0.97 +/- 0.81 micrograms/ml and steady-state salivary and nasal se...